Fitz: You're drunk.
Mellie: That's impossible. A lady never gets drunk.
Fitz: You're drunk, Mellie.

Cyrus: You're evil.
Mellie: You're welcome.

The upsetting thing about being as educated as I am and as intelligent as I am is that being the First Lady is profoundly boring.

Mellie: They want to go public.
Cyrus: Aren't you part of 'they' now? One-third of some secret, unholy political trinity.

Mellie: That is not you cheating on me. That is you...
Fitz: That is me being in love with another woman.

Mellie: Tell Fitz he has 36 hours to convince me in person that he regrets the unfortunate choices he's made and truly wants to recommit himself to his wife and children. If he doesn't, he will have the pleasure of seeing the First Lady of the United States call her husband a whore-loving bastard on national television.
Cyrus: You wouldn't.
Mellie: Call my bluff, Cy. I dare you.

Fitz: Does it ever bother you? All the lies? All the pretending? And that's not an accusation, cause I do it too and do it well. It's just a question. Because it's gotten so easy. I don't know anymore.
Mellie: Pretending is what's real.
Fitz: What?
Mellie: Every married couple alive pretends. They pretend they don't hate their in-laws or their husband's stupid jokes or their wife's laugh or that they don't actually love one of their children more than the others. Marriage is, well, it's almost all pretend. For everyone. That's the reality. That's what's real. Buying into the delusion that there's any other way to live together, to get through an entire life together, that's, well that's the fantasy. That's pretending.

You're not their father anymore. And you're not Fitz anymore. You know who you are? You know who you've become? You're Big Jerry. You're your father. Everybody in this White House, Cyrus and me included, tiptoe around trying to figure out how to get on your good side. But you don't have a good side. You've turned into your father. So, you should understand how your children feel considering how much you hated your dad. They didn't want to come and so I told them they didn't have to. Deal with it. Put another glass of scotch on top of it and just deal with it.