May gave specific instructions, you go on a date with a crazy wall I have to chaperone.

Skye

Mack: Look I know you two have a past but from what I've seen the only thing that makes him worse is you.
Simmons: I know, why do you think I left?

Senator Ward: The American people are looking for a simple enemy Mr. Coulson. It's what makes them feel safe.
Coulson: And how do you think they'd feel if they knew your brother was HYDRA? That's an awfully complicated idea to grasp. Especially in an election year.
Senator Ward: Are you threatening me Mr. Coulson?
Coulson: No, I'm telling you I have your brother in my basement.

She can handle it. Deception's her forte. I mean that sincerely, not passive-aggressively. As in it's a good attribute for a spy.

Hunter

Guess being a douchebag runs in the family.

Skye

Coulson: I don't know how else to explain it but it needs to be carved.
Skye: Does it just appear in your mind like some sort of vision?
Coulson: No, it just kinda happens. Which is really frustrating because no matter how much I carve it still means nothing to me. I don't even have a theory.
Skye: I do. It's a map.

Skye: Hold on are you saying that I am an alien?
Coulson: It's a theory.
Skye: No a theory is what scientists use to prove things in nature. This is you telling me that I might be an alien. That is not something you just say like it's no big deal.
Coulson: I was trying not to rattle you.
Skye: Guess what? Epic fail.

To be honest I was almost relieved when SHIELD put him down. The Garrett I knew was long gone since the writing started. And whatever took his place, I don't think it was meant to survive.

Ward

Simmons: Fitz this is a good thing. You've got friends now, real friends you don't need me anymore.
Fitz: Yeah but I miss you. I mean, I still miss her.

You know keeping her in the dark won't end well.

May

Fitz: So I don't have an ex, but there was this girl that I like and I told her how I felt. But she doesn't feel the same way as I do, so she left.
Hunter: Her loss then mate. From what I can see she's missing out.

I know there's writing on the back of that painting. The government wouldn't have sent me down here if we didn't. Phil, you're the only one who can help me figure out what that writing is. It's what you do. Why don't we help each other out?

Talbot

Agents of S.H.I.E.L.D. Quotes

The world is full of evil, lies, pain, and death and you can’t hide from it. You can only face it. The question is when you do, how do you respond, who do you become?

Coulson

Discovery requires experimentation and this experiment will take time.

Whitehall