Penny: Promise me that you'll never go back to that island again.
Desmond: Why in God's name would I want to go back there?

Sawyer: Why didn't you shoot him?
Locke: Because he's one of my people.

Thank you Lord! ... I take that back!

Sawyer

Jack: I need to know that you're with me.
Kate: I have always been with you.

[to Kate] It's time to prepare yourself; you are going to lose the boy.

Norton

She's right. It was me. Sorry.

Ben

Miles: I've never been here before two weeks ago.
Daniel: Are you sure about that?

I have to make them come back, even if it kills me.

Locke

Locke: Don't you want them to come back? Don't you want her to come back?
Sawyer: Doesn't matter what I want.

The only side he's on is his own.

Sayid

This is all happening because they left. I think it will stop if I can bring them back.

Locke

Why there is a dead Pakistani on my couch?

Hurley's mom

Lost Quotes

Find a suitcase. If there's anything you want in this life, pack it in there, because you're never coming back.

Ben [to Jack]

Why there is a dead Pakistani on my couch?

Hurley's mom