No one calls me Moon Pie but Meemaw!

Sheldon

Sheldon: You won the Nobel prize, what, three years ago? So you must deal with a whole lot of "what has Smoot done lately?" My thought is we continue my research as team, you know, Cooper-Smoot, alphabetical.. When we win the Nobel Prize, you'll be back on top
Dr. Smoot: With all due respect, Dr Cooper, are you on crack?
Sheldon: Fine, Smoot-Cooper, what a diva

Hi, I'm the small package good things come in

Wolowitz [to Sumemr Glau]

Normally, around women he has the personality of a boiled potato. Put one beer in him, and he has the personality of M. Knight Charmalarmalon

Wolowitz [about Raj]

Leonard: Well, it seems once again you're caught between a rock and a crazy place.
Sheldon: Oh, I hate when that happens.

Wolowitz: Unlike you, I can actually talk to women while I'm sober.
Raj: You fail to take into account that even mute, I am foreign and exotic, while you on the other hand, are frail and pasty.
Wolowitz: Well ... you know the old saying: "Pasty and frail, never fail"

I have eleven hours with her in a confined space. Unless she's willing to jump off a moving train and tuck and roll down the side of a hill, she will eventually succumb to the acquired taste that is Howard Wolowitz

Wolowitz [about Summer Glau]

The Big Bang Theory Season 2 Episode 17 Quotes

Wolowitz: Unlike you, I can actually talk to women while I'm sober.
Raj: You fail to take into account that even mute, I am foreign and exotic, while you on the other hand, are frail and pasty.
Wolowitz: Well ... you know the old saying: "Pasty and frail, never fail"

I have eleven hours with her in a confined space. Unless she's willing to jump off a moving train and tuck and roll down the side of a hill, she will eventually succumb to the acquired taste that is Howard Wolowitz

Wolowitz [about Summer Glau]