The first of a two-part season finale finds Izzie fighting for her life as Mark and Owen contemplate their future relationships and careers.
We spend our whole lives worrying about the future, planning for the future, trying to predict the future, as if figuring it out will cushion the blow. But the future is always changing. The future is the home of our deepest fears and wildest hopes. But one thing is certain when it finally reveals itself. The future is never the way we imagined it.Meredith (closing voiceover)
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When something begins, you generally have no idea how it's going to end. The house you're going to sell becomes your home, the roommates you were forced to take in become your family and the one night stand you were determined to forget becomes the love of your life.Meredith (opening voiceover)
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