Grey's Anatomy Season 5

"Now or Never"

The fifth season concludes with George making a stunning announcement, Bailey questioning her pediatric fellowship program, and Izzie's fate hanging in the balance.

"Here's to the Future"

The first of a two-part season finale finds Izzie fighting for her life as Mark and Owen contemplate their future relationships and careers.

"What a Difference a Day Makes"

As Grey's Anatomy turns 100, Meredith and Derek prepare to walk down the aisle as Izzie's condition brings back familiar (handsome!) symptoms.

"No Good at Saying Sorry (One More Chance)"

As preparations continue for Meredith and Derek's wedding, her father returns to make amends. Izzie receives a visit from one of her estranged parents, as well.

"Sweet Surrender"

Izzie plays wedding planner to take her mind off her treatment, while Callie introduces Arizona to her disapproving father, and Owen seeks help for his PTSD.

"Elevator Love Letter"

Derek returns to the OR after his meltdown, while Izzie's condition requires her to undergo an operation of her own.

"Stand By Me"

Cristina and Izzie debate what do to next, while Mer attempts to get Derek out of the woods and back to work.

"I Will Follow You Into the Dark"

Derek decides to quit, but Meredith refuses to give up on him. Bailey and the Chief continue to bicker, while Izzie's interns discover something unsettling.

"An Honest Mistake"

Derek and Addison square off yet again - this time with a patient's life in the balance. Bailey, meanwhile, is stunned by Richard's recommendation letter.

"Before and After"

Addison, Naomi and Sam rush to Seattle Grace with Archer and reunite with old friends Derek and Mark. Izzie employs her fellow doctors in a medical game. Owen runs into someone from his past.

"Beat Your Heart Out"

In "Beat Your Heart Out," Derek searches for the best way to pop the question to our girl, while Little Grey wants to go public with Big Sloan.

"Stairway to Heaven"

As a patient's condition becomes more and more dire, Bailey becomes more and more desperate to do something - anything - to save him.

"Sympathy for the Devil"

Death row inmate William is still around and he's shaking things up, while Derek's mother comes to Seattle Grace and meets Meredith for the first time.

"Wish You Were Here"

Grey's Anatomy returns from its holiday hiatus with its 11th episode of Season Five.

"All By Myself"

Dr. Yang is forced to give up the coveted solo surgery, while sparks between Mark and Lexie possibly heat up.

"In the Midnight Hour"

Why the heck are the interns cutting themselves? And why the heck is Izzie still seeing Denny? And what happens when it all goes wrong?

"These Ties That Bind"

As if this season weren't turbulent enough, it's time for a couple of newcomers - Harriet Dixon and intern Sadie - to make their debuts and shake things up at Seattle Grace.

"Rise Up"

The sudden revelation that this is Brooke Smith's (Erica Hahn) last episode has dominated the discussion and speculation of this episode so far.

"Life During Wartime"

Empowered by the Chief, Bailey has new responsibility and the new head of trauma - Owen Hunt - is shaking things up at Seattle Grace.

"There's No 'I' in Team"

Mark talks with Callie about love. Seriously. Bailey heads a risky surgery - even by Seattle Grace standards. Derek gets sole credit for a tumor study he and Mer did.

"Brave New World"

Meredith freaks when Derek discovers her mother's diary, Callie preps for a date with Erica, and Cristina stumbles into a new part of the hospital.

"Here Comes the Flood"

In case the title didn't give it away, Seattle Grace is hit by a flood in this episode. Or more accurately, a plumbing fiasco.

"Dream a Little Dream of Me"

Meredith and Derek soon discover that 'happily ever after' isn't that easy, a military doctor, Dr. Owen Hunt, catches Cristina's eye, an...

Show:
Grey's Anatomy
Season:
5
Air Dates:
to
Total Episodes:
23

Grey's Anatomy Season 5 Quotes

[narrating] We all remember the bed time stories of our childhood. The shoe fit Cinderella, the frog was turned into a prince, sleeping beauty was awakened with a kiss. Once upon a time and then they lived happily ever after. Fairy tales. The stuff of dreams. the problem is, fairy tales don't come true. It's the other stories. The ones that start in dark and stormy nights and end in the unspeakable. The nightmares always seem to become the reality.

Meredith

Meredith: What happened!?
Cristina: A bus in front of him hit a telephone pole. He tried to swerve and miss it, but ...
Meredith: How bad is it?
Richard: Meredith -
Cristina: Meredith, you're gonna have to be strong.