19 Most Epic Grey's Anatomy Episodes

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Grey's Anatomy has aired 10 seasons' worth of episodes from 2005-present. Here, we've picked out the 19 most emotional, OMG-worthy and otherwise notable installments of the long-running medical drama.

1. A Hard Day's Night

A Hard Day's Night
The series opens with Meredith removing a sofa pillow from the bare bottom of a man named Derek. The rest is history.

2. Freedom

Freedom
As the fourth season finale gets underway, Meredith Grey works with Dr. Wyatt to understand what her mother was trying to tell her. By the time it ends, she has found catharsis, and her partner in life.

3. Map of You

Map of You
This Derek-centric hour was one of the high points of Season 10 so far, proving that the show's still got it.

4. Beautiful Doom

Beautiful Doom
As much as we love the majority of the collective cast, there is just something electric when the story is centered on Meredith and Cristina, as this Season 9 installment proved.

5. Dark Was the Night

Dark Was the Night
Henry passed and Teddy doesn’t know. Mer and Alex are stuck in the rain with a newborn and some bodies in the street. Cristina realized who she performed surgery on... and the news came that Zola is not coming back. Shonda tugged at our heartstrings on this one.

6. Adrift and at Peace

Adrift and at Peace
This installment was heartbreaking, emotional, well-paced, dramatic and a perfect sendoff for (hopefully) better things to come.

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Grey's Anatomy Quotes

CRISTINA: "There's a club. The Dead Dads Club. And you can't be in it until you're in it. You can try to understand, you can sympathize. But until you feel that loss... My dad died when I was nine. George, I'm really sorry you had to join the club."
GEORGE: "I... I don't know how to exist in a world where my dad doesn't."
CRISTINA: "Yeah, that never really changes."

MEREDITH: "You don't get to call me a whore. When I met you, I thought I had found the person that I was going to spend the rest of my life with. I was done! All the boys and all the bars and all the obvious daddy issues, who cares? I was done. You left me. You chose Addison. I'm all glued back together now. I make no apologies for how I chose to repair what you broke. You don't get to call me a whore."
DEREK: "This thing with us is finished. It's over."
MEREDITH: "Finally."
DEREK: "Yeah, it's done."
MEREDITH: "It is done."