19 Most Epic Grey's Anatomy Episodes

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Grey's Anatomy has aired 10 seasons' worth of episodes from 2005-present. Here, we've picked out the 19 most emotional, OMG-worthy and otherwise notable installments of the long-running medical drama.

1. A Hard Day's Night

A Hard Day's Night
The series opens with Meredith removing a sofa pillow from the bare bottom of a man named Derek. The rest is history.

2. Freedom

Freedom
As the fourth season finale gets underway, Meredith Grey works with Dr. Wyatt to understand what her mother was trying to tell her. By the time it ends, she has found catharsis, and her partner in life.

3. Map of You

Map of You
This Derek-centric hour was one of the high points of Season 10 so far, proving that the show's still got it.

4. Beautiful Doom

Beautiful Doom
As much as we love the majority of the collective cast, there is just something electric when the story is centered on Meredith and Cristina, as this Season 9 installment proved.

5. Dark Was the Night

Dark Was the Night
Henry passed and Teddy doesn’t know. Mer and Alex are stuck in the rain with a newborn and some bodies in the street. Cristina realized who she performed surgery on... and the news came that Zola is not coming back. Shonda tugged at our heartstrings on this one.

6. Adrift and at Peace

Adrift and at Peace
This installment was heartbreaking, emotional, well-paced, dramatic and a perfect sendoff for (hopefully) better things to come.

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Grey's Anatomy Quotes

Amelia: I think I'm falling in love with Owen Hunt, and I'm really afraid that it's gonna destroy me.
Derek: It wouldn't be love if it didn't.

When we say things like "people don't change" it drives scientist crazy because change is literally the only constant in all of science. Energy. Matter. It's always changing, morphing, merging, growing, dying. It's the way people try not to change that's unnatural. The way we cling to what things were instead of letting things be what they are. The way we cling to old memories instead of forming new ones. The way we insist on believing despite every scientific indication that anything in this lifetime is permanent. Change is constant. How we experience change that's up to us. It can feel like death or it can feel like a second chance at life. If we open our fingers, loosen our grips, go with it, it can feel like pure adrenaline. Like at any moment we can have another chance at life. Like at any moment, we can be born all over again.

Meredith