Devo guest stars as a musical guest and plays "Beautiful World" during the Futurama 100th episode. Oh and they're mutants on the show.
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A clip from the Futurama season finale in which the Planet Express crew makes its hundredth delivery.
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Futurama is returning to Comedy Central. It will air new episodes in the summer of 2010.
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Futurama Quotes

Farnsworth: (on the phone) Oh, how awful. Did he at least die painlessly? To shreds, you say. Well, how is his wife holding up? To shreds, you say. Very well then. (hangs up) Sad, sad, terrible, gruesome news about my colleague, Dr. Mobutu.
Leela: Was his apartment rent-controlled?

Oh, why couldn't she be the other kind of mermaid, with the fish part on the top and the lady part on the bottom?

Fry