Devo guest stars as a musical guest and plays "Beautiful World" during the Futurama 100th episode. Oh and they're mutants on the show.
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A clip from the Futurama season finale in which the Planet Express crew makes its hundredth delivery.
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Futurama is returning to Comedy Central. It will air new episodes in the summer of 2010.
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Futurama Quotes

Farnsworth: (on the phone) Oh, how awful. Did he at least die painlessly? To shreds, you say. Well, how is his wife holding up? To shreds, you say. Very well then. (hangs up) Sad, sad, terrible, gruesome news about my colleague, Dr. Mobutu.
Leela: Was his apartment rent-controlled?

Fry: Professor, my Fry-fro's all frizzy.
Farnsworth: Okay?
Fry: That's all. Oh, also, I'm covered in severe burns.
Farnsworth: So, what of it?
Fry: Well...why is...those things?
Farnsworth: You mean you don't remember?
Fry: Nope, nothing. It's like when I passed out in college except nobody drew magic marker penises on my forehead