Watson: There's just one question I want to ask you about your past.
Sherlock: Excellent, you wait here and I'll go to my room, shut the door. Soon as you're absolutely certain I can't hear you, ask away.

I know about Irene. I want you to tell me about her.

Watson

Did you enjoy your time with dear old dad? Come on Watson show some appreciation for a prank well played.

Sherlock

Sherlock: You should have trusted me when I told you he wouldn't show.
Watson: Trusted you? I've been glued to your side for weeks now and you've refused to show even the tiniest bit of your personal history. You know what Sherlock, I don't trust because thanks to you we're basically still strangers.

I've had many clients but Sherlock is definitely the most unique. I would like to know more about him.

Watson

Allistair: How's the sex?
Watson: I beg your pardon
Allistair: Sex. Shagging? Is he enjoying it?
Watson: I don't undertand.
Allistair: I heard that was part of the service you provided. Satisfying your clients every need why else would anyone pay your exuberant fees?

Joan: Part of recovery is addressing painful things. If you ignore them they become triggers.
Sherlock: Could you shoot me all of this in an email? I'm much better at processing the written word.

Sherlock: You're right, I have been cutting you off. The demands too sulking and it is no way to conduct an adult relationship. I might not like what you did but I suppose I have to respect you're right to do it. I would propose a toast to our new spirit of collaboration but I neglected to pour myself a coffee. Would you mind waiting a moment?
Watson: Of course.
[Sherlock leaves the house]

Coming in here this morning was like walking into a nightmare that I thought I stopped having a long time ago.

Gregson

Sherlock: I sent you a text with my location every two hours.
Joan: I was busy.
Sherlock: I left some urine in your room.
Joan: Tell me it's in a cup...

Sherlock: She died.
Watson: Irene?
Sherlock: We were quite close, I did not take her passing well.

Watson: How do you do it, guess things?
Sherlock: I observe and then I deduce.
Watson: How did you know I was a doctor, you said you could tell from my hands.
Sherlock: Hand, singular. It was soft no calluses.
Watson: How did you know my father had an affair?
Sherlock: Google. Not everything is deducible.

Elementary Quotes

Holmes: Why do you suppose you hate your job so much?
Watson: I don't hate my job.
Holmes: You have two alarm clocks. No one with two alarm clocks loves their job. Two alarm clocks mean it's a chore for you to get up in the morning.

Watson: How do you do it, guess things?
Sherlock: I observe and then I deduce.
Watson: How did you know I was a doctor, you said you could tell from my hands.
Sherlock: Hand, singular. It was soft no calluses.
Watson: How did you know my father had an affair?
Sherlock: Google. Not everything is deducible.