Derek watches Zola put applesauce in her ear and he's enchanted.

Cristina

IZZIE: "Denny, um... I'm giving you an out."
DENNY: "Excuse me?"
IZZIE: "Well, I'm giving you an out. You thought you were dying and I was saving your life and well, you know, it was so... We cant get married. I mean that would be insane. We should date, and have sex. Plenty of sex. You know when your heart gets better and you're out of the hospital, all the sex you can handle. But marriage is... well, marriage."
DENNY: [smiles] "It's my turn now."
IZZIE: "But I need to-"
DENNY: "No, no. We're taking turns. I've decided. It's polite and it keeps me from yelling. When it's your turn again, you can talk. For five years, I've had to live by the choices of my doctors. The guys that cut me open decided my life. There wasn't one choice that was mine. Now, I have this heart that beats, that works. I get to be like everybody else, I get to make my own decisions, have my own life, do whatever the damn hell I choose. Now here's the good part, so you listen close. What I choose... is you. You're who I want to wake up with and go to bed with and do everything in between with. I get a choice now. I get to choose. I choose you, Izzie Stevens. Okay, it's your turn again."

Somethings are simply out of your control. You can't change them, you can't bend them to your will.

Meredith

PRESTON: [enters his apartment] "I am Preston Burke. I am a widely renowned cardio-thoracic surgeon. I am a professional and moreover I am a good, kind person. I am a person that cleans up after himself. I am a great cook. And you? You are an unbelievable slob. A slovenly, angry intern. I am Preston Burke. And you... are the most competitive, guarded, stubborn... the most challenging person I have ever met. And I love you. Why the hell won't you just let me?
CRISTINA: "I gave up my apartment 20 minutes ago."
PRESTON: [pauses] "Well, alright then."

You feel terrible? You took advantage, he was your best friend. I tried to trust you. So much that I convinced myself that it was all in my head, that I was crazy. But I wasn't, was I? And then you pulled that thing in the cafeteria today. It's not bad enough that you humiliate me by getting in bed with my husband, you have to humiliate me at work too. George may be the one who broke his vows but you... we're women, Izzie. You did this to another woman. You took something from me. You stole something from me like a petty little thief. YOU are the one who should be humiliated. YOU are the one who should be ashamed. You are the one... don't you dare come to me for forgiveness you traitorous bitch.

Callie

"Dude, she's Callie O'Malley."

ALEX

You're right, Cristina. I'm not your person and either is Owen. Your person is you. It always has been.

Meredith

Izzie: You never know the biggest day of your life is the biggest day. Not until it's happening. You don't recognize the biggest day of your life, not until you're right in the middle of it. The day you commit to something or someone. The day you get your heart broken. The day you meet your soul mate. The day you realize there's not enough time, because you wanna live forever. Those are the biggest days. The perfect days. You know?
Denny: I bet you ... you made a beautiful bride.
Izzie: It was a beautiful day.
Alex: You put the scarf on. I told you, you don't need it. You look gorgeous without it.
Denny: He's right.
Izzie: Go away now. Go away, I wanna be alone with my husband.
Alex: (Takes off her scarf, and kisses her forehead) My wife is hot!
(Izzie giggles and smiles)

DEREK: "Seattle has ferryboats?"
MEREDITH: "Yes."
DEREK: "I didn’t know that. I've been living here six weeks, and had no idea there were ferryboats."
MEREDITH: "Seattle is surrounded by water on three sides."
DEREK: "Hence the ferryboats. Now I have to like it here. I wasn’t planning on liking it here, since I'm from New York, and am genetically engineered to dislike everywhere except Manhattan. But I do have a thing for ferryboats."
MEREDITH: "I'm not going out with you."
DEREK: "Did I ask if you'll go with me? Do you want to go out with me?"
MEREDITH: "I'm not dating you and I'm definitely not sleeping with you again. You're my boss."
DEREK: "No, I'm your boss' boss."
MEREDITH: "You're my teacher and my teacher's teacher. And my teacher!"
DEREK: "I'm your sister. I'm your daughter."
MEREDITH: "You're sexually harassing me."
DEREK: "I'm just riding in an elevator."
MEREDITH: "Look, I'm drawing a line. The line is drawn. Thereis now a big line."
DEREK: "So this line... is it imaginary or do I need to get you a marker?"

GEORGE: "Why is he suturing his own face?"
CRISTINA: "To turn me on..."
ALEX: "Because he's Mark Sloan. The guy is like the go-to plastic surgeon on the east coast."
GEORGE: "That’s the guy Addison was sleeping with."
IZZIE: "Can you really blame her?"
CRISTINA: "No, not really."
GEORGE: "Yes, you can."
MEREDITH: "Well McSexy wants an X-ray to check for fractures and I think it’s a bad idea if I go with him."
GEORGE: "Why?"
ALEX: "I'm on it."
GEORGE: "Why is that a bad idea?"
CRISTINA: "McSexy?"
MEREDITH: "That's not right."
IZZIE: "McYummy?"
CRISTINA: "Mmm... no."
MEREDITH: "McSteamy."
CRISTINA: "There it is!"
IZZIE: "Yup."
GEORGE: "Allow me to choke back some McVomit."

They say death is hardest on the living. It's tough to actually say goodbye. Sometimes it's impossible. You never really stop feeling the loss. It's what makes things so bittersweet.

Meredith

Always had to be the first.

Derek to Mark
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Grey's Anatomy Quotes

[walking by Izzie's room]
Meredith: Hot.
Sadie: Horny.

Sexual sorbet? Hahaha! I love it.

Bailey