Your body hurts. Your brain becomes foggy. And you feel like you're trapped in a tunnel, when all you want is your bed. So, how do you keep going? How do you not just sit down and give up? Sometimes it's easy. Sometimes you play games in your head. You make up someone. Someone good. Whatever you need to keep you going.

Meredith

Derek: I wanna be with you forever, and you wanna be with me forever. In order to do that we need to make vows. A commitment. A contract. Give me a piece of paper.
Meredith: I don't! I... I... I don't. I have post its!
Derek: (takes the post its and a pen) Ok. What do we wanna promise each other?
Meredith: That you'll love me... even when you hate me.
Derek: To love each other, even when we hate each other. (writes it down) No running. Ever! (Mer smiles and comes and sits in front of him) Nobody walks out. No matter what happens.
Meredith: No running.
Derek: (writes it down) What else?
Meredith: That we'll take care of each other, even when we're old, and smelly, and senile. And... if I get Alzheimer's and forget you...
Derek: I will remind you who I am, every day. To take care when old, senile, and smelly (writes it down) This is forever. (signs it) Sign.
Meredith: This is our wedding. A post it? (smiles)
Derek: Mhmmm. If you sign it.
Meredith: (signs it, and hands it back. Has tears in her eyes) Now what?
Derek: Now I kiss the bride. (They kiss)
Meredith: (smiling) Married.
Derek: (smiling) Married. (sticks their post it in Mer's locker) You see that? (Mer nods and smiles) Plenty of time.

"People die in front of us everyday. But I believe Meredith will survive this. I believe, I believe, I... I believe in the good. I believe that it's been a hell of a year and I believe that, in the face of overwhelming evidence to the contrary, that we will be okay. I believe a lot of things. I believe that... I believe that Denny is always with me... and I believe that if I eat a tub of butter and no one sees, that the calories don't count. And I believe that surgeons who prefer staples over stitches are just lazy. And I believe that you are a man that made a terrible mistake marrying Callie and I believe that because I'm your best friend I can tell you this and we can be okay. I believe that even though you made this mistake you will be okay. I believe we survive, George. I believe that believing we survive... is what makes us survive."

IZZIE

Richard: Chin up. Put your shoulders back, walk proud, strut a little. Don't lick your wounds: celebrate them. The scars you bear are the signs of a competitor. You're in a lion fight, Stevens. Just because you didn't win doesn't mean you don't know how to roar.

Sometimes the future changes quickly and completely, and we’re left with only the choice of what to do next. We can choose to be afraid of it, to stand there trembling not moving, assuming the worst that can happen or we step forward into the unknown and assume it will be brilliant.

Cristina

Marriage is like a bed and breakfast in Vermont with sex.

Amelia

Lexie: Are you really gay? Like, how gay are you? On a scale of 1 to gay? 'Cause that's my boyfriend in the shower. My hot, hot, naked boyfriend and I... How gay are you?
Callie: I'm sorry. It's... I've known Mark a while and... But, I'll try not to do that again. The naked in the shower thing.
Lexie: Or, the you half naked in the hallway thing. Cause, cause even if you really are gay. He's not, and you're hot.
Callie: He doesn't look at my boobs anymore. The first thing he used to look at when I walked into anywhere, was my boobs. He doesn't look anymore. Not since he met you. Ok?
Lexie: Ok.

The brain is the human body's most mysterious organ. It learns. It changes. It adapts. It tells us what we see, what we hear. It lets us feel love. I think it holds our soul. And no matter how much research we do, no one can really say how all that delicate grey matter inside our skull works. And, when it's hurt, when the human brain is traumatized, well, that's when it gets even more mysterious.

Callie

[narrating] "The early bird catches the worm; a stitch in time saves nine. He who hesitates is lost. We can't pretend we haven't been told. We've all heard the proverbs, heard the philosophers, heard our grandparents warning us about wasted time, heard the damn poets urging us to ‘seize the day'. Still sometimes we have to see for ourselves. We have to make our own mistakes. We have to learn our own lessons. We have to sweep today's possibility under tomorrow's rug until we can't anymore, until we finally understand for ourselves like Benjamin Franklin meant. That knowing is better than wondering, that waking is better than sleeping. And that even the biggest failure, even the worst most intractable mistake beats the hell out of never trying."

MEREDITH

"Do you know what kind of miracle it is that Derek is who he is? Do you know how rare it is that someone like him even exists? He's still an optimist! He still believes in true love and magic and soulmates. He's waiting for you. And if you don't come back from this, you will change who he is."

DENNY

I don't have to say a word. She just looks at me and sees who I am and how I feel and accepts it. She doesn't try to change it or wants to change it. That person. There's a billion people but I imagine there's only one of her.

Owen

Lexie: You have to stop. You gotta stop talking to me and checking on me and talking to my boyfriend. I love you, and I'm always gonna love you, but I don't want to love you. I want to be happy, and Jackson makes me happy. And if you keep pulling at me, I'll come back to you.
Mark: You're right, I'm sorry.
Lexie: You got what you wanted you wanted a family so please just let me have what I wanted.
Mark: I said you're right. I told Avery I was letting you go. Did he tell you that part?
Lexie: Yes, it's paternalistic and weird.
Mark: I'm letting you go, Lexie. That means you've got to walk away.

Grey's Anatomy Quotes

MEREDITH: "You don't get to call me a whore. When I met you, I thought I had found the person that I was going to spend the rest of my life with. I was done! All the boys and all the bars and all the obvious daddy issues, who cares? I was done. You left me. You chose Addison. I'm all glued back together now. I make no apologies for how I chose to repair what you broke. You don't get to call me a whore."
DEREK: "This thing with us is finished. It's over."
MEREDITH: "Finally."
DEREK: "Yeah, it's done."
MEREDITH: "It is done."

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)