Don't wonder why people go crazy. Wonder why they don't. In face of what we can lose in a day, in an instant, wonder what the hell it is that make us hold it together.

Meredith

ADDISON: "There is a land called Passive Agressiva, and I am their queen."
DEREK: [smiles] "That's all I'm saying... except when you're shrieking about trout."

Sometimes the future changes quickly and completely, and we’re left with only the choice of what to do next. We can choose to be afraid of it, to stand there trembling not moving, assuming the worst that can happen or we step forward into the unknown and assume it will be brilliant.

Cristina

Just because we can live without something, it doesn't mean we have to.

Meredith

Just when we think we figured things out, the universe throws us a curveball. So, we have to improvise. We find happiness in unexpected places. We find ourselves back to the things that matter the most. The universe is funny that way. Sometimes it just has a way of making sure we wind up exactly where we belong.

Meredith

She caught a fish and cried is not the whole story.

Meredith

Richard: Chin up. Put your shoulders back, walk proud, strut a little. Don't lick your wounds: celebrate them. The scars you bear are the signs of a competitor. You're in a lion fight, Stevens. Just because you didn't win doesn't mean you don't know how to roar.

Owen: It's a cute baby, right?
Cristina: Its small features and oversized thighs trigger a hormonal response from humans. It's autonomic. It's what keeps us from eating them.

Callie: Did anyone ever think you two were a couple?
Meredith: No, because we screw boys like whores on tequila.
Cristina: Then we either try to marry them or drown ourselves.
Callie: Huh.

IZZIE: "I'm a pretty girl."
RICHARD: "What?"
IZZIE: "I'm not being arrogant, it's just, it's just kind of a fact. For a long time I made a career from my looks, so I get it, I'm a pretty girl. And not in a 'from a certain angle' way, in an obvious way. It’s the blonde thing and the big boobs thing. Big boobs are a key to 'obvious pretty' if you know what I'm saying."
RICHARD: "Dr. Stevens-"
IZZIE: "It's how men see me. I'm not a smart girl or an interesting girl, I'm a pretty girl. The blonde and the boobs, it confuses guys into thinking I'm someone else. And I'm used to it. And I'm used to them walking away when they realize… But then Denny goes and asks me to marry him."
RICHARD: "Is that why you cut the wires?"
IZZIE: "He doesn't make me feel like I'm a pretty girl. He makes me feel like… like me. I think he might know me. And so, if I did cut the LVAT wire, and I'm not saying that I did, but if I did, then no. I don't feel guilty. I know that I should. I would if it were anybody else's. But I can't feel anything but happy."

[to Richard] "Let's say you were drafted to a team that wasn’t your first pick. You know, you don't like the players. You hate the way they play the game. You even think the quarterback is full of crap. The quarterback's a pain in the ass you don't owe a damn thing to. But, it's your team. You don't quit. You don't talk to the press. You don't bitch to the coach. You just... you go out there on Sunday and you make the blocks and you take the hits and you play to win. You show up and you suit up and you play, because it's your freaking team."

ALEX

Meredith: You're better than this. You're stronger.
Amelia: Don't make this all your fault. I know you. That's what you do. But, please. Please don't do that.
Maggie: We can't just give up, not after all this time. We have to stand together. We have to fight.
Meredith: Because it's just us now. There were five of us, and now it's just you and I. And it can't be just me. It can't be. I will go down swinging for you, Alex. You know I will. But that means you can't give up. You don't throw the fight. So, whatever you're doing this for... please don't.

Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

There's a reason I said I'd be happy alone. It wasn't 'cause I thought I'd be happy alone. It was because I thought if I loved someone and then it fell apart, I might not make it. It's easier to be alone, because what if you learn that you need love and you don't have it? What if you like it and lean on it? What if you shape your life around it and then it falls apart? Can you even survive that kind of pain? Losing love is like organ damage. It's like dying. The only difference is death ends. This? It could go on forever.

Meredith