Mark: You're never at a loss for words with your patients. You never hesitate to tell me how you feel. So why not tell O'Malley.
Lexie: You are the last person who should be giving romantic advice.
Mark: When I like somebody I make sure they know it. Life's too short to live any other way.

Rose: I'm sorry about the hand.
Derek: These things happen.
Rose: Not to me they don't. Or they didn't, before you existed for me.

I'm carrying your child, Derek.

Rose

Miranda: Dr. Karev. What time is it?
Alex: Tomorrow. His insurance expired.

[to patient] It happens. People make mistakes. They ... sleep with the wrong person and ... they hide it but, if you ask me, it's the part that comes after that matters. The part where you make it right. And I think you're off to a good start.

Lexie

[narrating] Reality. It's so much more interesting than living happily ever after.

Meredith

The surgical training protocol is officially being changed, people. The bar has been raised. Consider yourselves on notice.

Richard

We're sloppy, just like everybody else. We've been resting on our laurels. You have all been failing. Failing to take initiative. Failing to ask tough questions. Failing to practice your skills. Failing to give opportunity TO practice skills. And I let it happen. So you have not failed. We have failed. Well, it stops, and it stops now.

Richard

[narrating] We all remember the bed time stories of our childhood. The shoe fit Cinderella, the frog was turned into a prince, sleeping beauty was awakened with a kiss. Once upon a time and then they lived happily ever after. Fairy tales. The stuff of dreams. the problem is, fairy tales don't come true. It's the other stories. The ones that start in dark and stormy nights and end in the unspeakable. The nightmares always seem to become the reality.

Meredith

Meredith: What happened!?
Cristina: A bus in front of him hit a telephone pole. He tried to swerve and miss it, but ...
Meredith: How bad is it?
Richard: Meredith -
Cristina: Meredith, you're gonna have to be strong.

Oooh! A trauma!

Izzie

Derek: I have to go.
Meredith: What?
Derek: In order to kiss you the way I wanna kiss you and in order to do more than kiss you I need to speak to Rose. I want my conscience clear so I can do more than kiss you. Stay here, don't move, wait for me.

Grey's Anatomy Quotes

[walking by Izzie's room]
Meredith: Hot.
Sadie: Horny.

Sexual sorbet? Hahaha! I love it.

Bailey