Meredith: I...uhm....
Derek: You're not ready for this.
Meredith: No.
Derek: I asked for too much.
Meredith: I think so.
Derek: So, this is it?
Meredith: Yeah.
Derek: We're breaking up?
Meredith: We're breaking up.

Alex: Callie's a bitch.
Izzie: Word!

Meredith: [narrating] Change; we don’t like it, we fear it, but we can't stop it from coming. We either adapt to change or we get left behind. And it hurts to grow, anybody who tells you it doesn’t is lying. But heres the truth: the more things change, the more they stay the same. And sometimes, oh, sometimes change is good. Oh, sometimes, change is ... everything.

Cristina: I have five rules. Memorize them. Rule number one, don't bother sucking up. I already hate you, that's not gonna change.
Izzie: Traumas protocol, phone lists, pagers. The nurses will page you, you answer every page at a run. A RUN! That's rule number two... You're supposed to follow me!
Alex: The first shift starts now and lasts 36 hours. You're grunts, nobodies, the bottom of the surgical food chain. You run labs, write orders, work every second night until you drop. And you don't complain.
Meredith: On call rooms. Sleep when you can, where you can. You know, but not with anybody. Not attendings, especially not attendings. Sleeping with attendings, not a good idea. Where was I?
George: Er, rule number three. If you're sleeping, do not wake you unless the patient is actually dying.
Cristina: The dying patient better not be dead when I get there, because not only will you have killed someone, you will have woken me for no good reason. Are we clear? Yes?
Lexie: That was four rules. You said five.
Cristina: Rule number five. When I move, you move... Go!

[last lines] "I love you too."

George

You're right. I'm not helping him, I'm helping Bambi.

Izzie

Derek: [to Lexie] You're the girl from the bar.
Meredith: Girl from the bar? I'm the girl from the bar!

I tell you that I love you, and not one word? For 17 days? Where have you been?

Izzie

[narrating] In the practice of medicine, change is inevitable. New surgical techniques are created, procedures are updated, levels of expertise increase. Innovation is everything, nothing remains the same for long. We either adapt to change, or ... we get left behind.

Meredith

ADDISON: "What was that for?"
PETE: "To remind you that you’re not dried up. If you need me to remind you again... lemme know."
ADDISON: "Okay."

PETE: "What’s wrong with flirting?"
ADDISON: "What’s wrong with it? What’s wrong? What’s wrong is that I don’t have time for it. I am out of time. I missed my chance. And now I have two eggs left, I might as well have no eggs left. I am egg-less. Naomi says she’s dried up? I’m the one who's dried up. I’m all barren and dried up. And I’m clearly wasting my time on men. I mean I might as well take up a hobby. Like needlepoint or collecting those ceramic dolls because that’s what dried up women do – they do needlepoint. They don’t waste there time flirting with men who clearly just want to get laid. They don’t waste their time telling overly personal information about their eggs to total strangers. Oh my God. I'm sorry."

"There you are. I just stopped by to see how Lisa and the baby are doing."

PETE

Grey's Anatomy Quotes

[walking by Izzie's room]
Meredith: Hot.
Sadie: Horny.

Sexual sorbet? Hahaha! I love it.

Bailey