CRISTINA: [to Mer, but everyone hears] "Are you pregnant?"
ADDISON: [to Derek] "An adulterous love child?"
DEREK: "Goes along with an adulterous sociopath."

RICHARD: "What kind of idiot lights a cigarette in a hospital?"
DEREK: "Apparently people do idiotic things all the time."

MEREDITH: [after throwing up] "I'm fine."
DEREK: "You're burning up. You don't look fine. You look beautiful, but you don't look fine."
CRISTINA: "Now I'm gonna throw up."

PRESTON: "I need more chickens."
CRISTINA: "No more chickens. Okay? It’s bad enough that Meredith is dating a vet, I am not dating a chicken surgeon."

DEREK: "Can I ask you a personal question? Why did you leave Meredith's mother?"
RICHARD: "I could have left Adele. I could have gone away with Ellis. But I would have had so much baggage, so much guilt. Ellis couldn't see it, but I wasn't... I would have never made her happy. Not like she was certain to be happy. I was a better man for walking away. I loved her enough to walk away."

MEREDITH: "If I did die today, I'd only be remembered as the slutty intern who dated two doctors."
CRISTINA: "No, one doctor and one vet."
MEREDITH: "Derek, Finn, Derek, Finn. I'd die as the girl who couldn't make a choice, right?"
CRISTINA: "Probably. But none of that matters, because you'll be dead."

MEREDITH: "You're a good friend."
CRISTINA: "So high right now."
MEREDITH: "Actually, you're my best friend in the whole entire world."
CRISTINA: "I just feel sorry for you."
MEREDITH: "Why? Because I could die today?"
CRISTINA: "This is why I hate being around stoned people."

[message / voiceover] "Dad, mom. It's me. I'm calling from Seattle Grace Hospital where the beautiful, talented and incredibly stubborn Dr. Isobel Stevens has... she's given me a brand new heart and promised to marry me. I know we've had our differences and I'm sorry we've been out of touch. Believe it or not, I was trying to make everything better. I know you're angry but I hope you'll forgive me. It turns out, sometimes you have to do the wrong thing. Sometimes you have to make a big mistake to figure out how to make things right. The stakes are painful. But they're the only way to find out who you really are. I know who I am now. And I know what I want. I've got the love of my life, a new heart and I want you guys to get on the next plane out here and meet my girl. Everything's going to be different now, I promise. From here on out, Nothing's every going to be the same. I love you, bye."

DENNY

DEREK: "You deserve to be with somebody who makes you happy. Somebody who doesn't complicate your life. Somebody who won't hurt you. He's the better guy. [pauses] Finn's the better guy."
MEREDITH: "Derek?"
DEREK: "I'm walking away."

MARK: "Can I buy you a drink, Dr. Torres?"
CALLIE: [gets up] "Not unless you have it delivered to my hotel room... I'm going to bed. You coming?"

"It’s always Meredith and Izzie. Never me. Who am I to you. George? Am I your girlfriend? Am I somebody to mess around with? Do you even know? Well, guess what. Now you don’t have to bother figuring it out."

CALLIE

"I guess there really is no starting over, is there?"

MARK

Grey's Anatomy Quotes

[walking by Izzie's room]
Meredith: Hot.
Sadie: Horny.

Sexual sorbet? Hahaha! I love it.

Bailey