[narrating] "How do you know how much is too much? Too much too soon. Too much information. Too much fun. Too much love, or too much to ask of someone? When is it all just too much for us to bear?"

MEREDITH

[narrating] "There's something to be said about a glass half full, about knowing when to say when. I think it's more of a floating line, a barometer of need. Of desire. It's entirely up to the individual, and it depends what's being poured. Sometimes all we want is a taste. Other times there's no such thing as enough, the glass is bottomless... all we want is more."

MEREDITH

GEORGE: "You know Joe?"
MIRANDA: "Oh, yeah. I was the only female intern my year. I didn't know anybody and nobody knew me except Joe. He knew me."
GEORGE: "Oh, so you and Joe..."
MIRANDA: "All you people ever think about is how to get into somebody's pants. You're nasty." [Slaps George] "That's why you got syphilis."
MIRANDA: "Oh come on. All you people ever think about is how to get into somebody's pants. You're nasty." [slaps George] "That's why you got syphilis."

CRISTINA: "Your problem is estrogen."
MEREDITH: "No, my problem is tequila."

MEREDITH: "I have this feeling."
DEREK: "I get that feeling also. If you wait long enough it will pass."
MEREDITH: "Do you promise?"
DEREK: "I promise."

[drunkenly narrating] "In general, people can be categorized in one of two ways. Those who love surprises and those who don't. I don't. I've never met a surgeon that enjoys a surprise, because as surgeons, we like to be in the know. We have to be in the know, because when we aren't, people die and lawsuits happen. Okay, I think I'm rambling. My point, actually, and I do have one, has nothing to do with surprises or death or lawsuits, or even surgeons. My point is that whoever said 'What you don't know can’t hurt you,' was a complete and total moron. Because for most people I know, not knowing is the worst feeling in the world." [sees passengers impaled on metal pole] "Okay, fine. Maybe the second worst."

MEREDITH

MEREDITH: "Hey."
DEREK: "Hey. You almost died today."
MEREDITH: "Yeah, I almost died today."
[pause]
MEREDITH: "I can't, I can't remember our last kiss. All I could think about was 'I'm going to die today' and I can't remember our last kiss. Which is pathetic but the last time we were together and happy... I want to be able remember that. And I can't, Derek. I can't remember."
DEREK: "I'm glad you didn't die today."
[pause]
DEREK: "It was a Thursday morning, you were wearing that ratty little Dartmouth t-shirt you look so good in. The one with the hole at the back of the neck. You'd just washed you hair and smelled like some kind of... flower. I was running late for surgery, you said you were going to see me later, and you lean to me, put your hand on my chest and you kissed me. Soft. It was quick. Kind of like a habit. You know, like we'd do it everyday for the rest of our lives. Then you went back reading the newspaper and I went to work. That was the last time we kissed."

[to Bailey's baby] "Shut it.... shut it!"

CRISTINA

MEREDITH: "If I tell you what I did, you have to react like you're my friend, not not my friend."
DEREK: "I think I can handle that."

DEREK: "I was indifferent."
ADDISON: "What?"
DEREK: "You know, in New York. Before Mark. I was indifferent towards you."
[pause]
ADDISON: "Yes."
DEREK: "I was absent."
[pause]
ADDISON: "Yes."
DEREK: "I'm partly to blame, for our marriage."
[pause]
ADDISON: "Yes."
DEREK: "I'm sorry... and I'm working on it."
ADDISON: "Okay."

RICHARD: "Yang, what is that smell?"
CRISTINA: "That's feces. Baby feces."

MEREDITH: I... I slept with George. I slept with him and it was a horrible mistake. Now everything has changed and I don’t know how to repair it. I don’t even know where to start, but I just know that I have to and..."
DEREK: [pauses] You tell him that. You find George and you apologize.
MEREDITH: "That’s what everyone’s saying but he wont listen."
DEREK: "You tell him you’re sorry. Just tell him again and again and again until he listens."
MEREDITH: "How do I make him?
DEREK: "Do what I do... use the elevator."

Grey's Anatomy Season 2 Quotes

IZZIE: "You want us to make her seize? How do we make someone have a seizure?"
DEREK: "Get creative. Do some research."
GEORGE: "Well, if all the normal methods have failed then what are we supposed to do-"
DEREK: "Use a strobe light. Get her drunk. Hang her up upside down from the ceiling and hit her with a wiffle ball bat, for all I care. Just make her seize. 'Cause until she seizes, I don't know when to operate, and if I don't know when to operate, I can't get this woman out of my life. And this woman is not how I like to start my mornings."

CRISTINA: "I am a 55 year old man. I'm nauseous and I can't stop throwing up."
ALEX: "Forget it, alright. I didn't ask for anybody's help."
CRISTINA: "Look, evil spawn, you can nurse your pride -- the key word being nurse -- or you can pass your test and be a doctor. Up to you."
ALEX: [pauses] "Any abdominal pain?"
CRISTINA: "Yes, from my giant fat belly all the way to my back. Oh, and I'm drunk. Hiccup. Hiccup."