My fingers are too full of beer. They barely work as it is.

Malloy

Perry: It's undeniable they've achieved something extraordinary. But I have to admit, I wish they hadn't.
Grayson: March of progress. Can't stop it.
Perry: The weaponization of time travel has always been the unthinkable horror. If the Krill or the Kaylon ever achieved it, they could skip the galactic brinkmanship and simply destroy the Union at its inception.

Isaac: If Commander LaMarr had not followed through with his intent to send the sandwich into the past, it would've caused a temporal paradox.
LaMarr: In which case, an entirely new universe would've branched off from this one all because of a sandwich.
Mercer: Makes your head hurt.

Malloy: Look, I know that there's nothing that's going to make you feel better, but for what it's worth, you did the right thing. As hard as it was, you put your duty first.
Mercer: Yeah, you're right, I don't feel better.

A family does powerful things to a person.

Grayson

No matter what, I will always love you both. Do you understand? Always. This family is stronger than Time.

Malloy

Without knowing, we can't interfere. We don't have the wisdom. We don't have the foresight.

Mercer

Laura: Gordon tells me that you work out of the Boston area. You must be Sox fans.
Grayson: Yeah, I mean it gets cold out there. So socks are...
Mercer: Socks are important.

Laura: I had just broken up with this guy, Greg, and the last thing that I wanted was another douchebag.
Malloy: But she went out with me anyway.
Laura: That's right, yeah. Look at us. Seven years later, that douchebag's my husband.
Malloy: I'm her douchebag.

I would give anything to be ignorant of my beginnings. Topa may never be happy, but unhappiness is better than despair.

Klyden

Grayson: I don't want to disrespect your religion, but maybe there's a sensible compromise between your faith and Union protocol that would satisfy everyone involved.
Bolobar: What do you suggest?
Grayson: Put some pants on and we'll call it a day.
Bolobar: Very well, Commander.

Yaphit: I just want you to know we always enjoy your visits down here.
Grayson: Thanks, Yaphit. [to Topa] Just for your own education, that's called ass-kissing.
Topa: Ass-kissing. Will it be on the entrance exam?

The Orville: New Horizons Quotes

Grayson: You’ve been getting harassed by the crew and you haven’t said anything?
Isaac: I would remind you, Commander, that I am incapable of being hurt by such hostile interactions. In fact, it has provided me with an opportunity to observe an intriguing facet of human compartment I have not previously encountered.
Mercer: Hatred.
Isaac: Correct, sir. The behavioral data has been quite plentiful.

It really is a shame that you can’t feel anything. Because you deserve to feel all the pain in the universe.

Burke