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Daisy tells Coulson about the Framework. Ward warns her that a Hydra unit is coming to get Coulson. Mack gets his daughter ready for school. Daisy brings Coulson to Simmons. Simmons offers to talk to Fitz but Daisy insists it's too dangerous. 

Daisy goes to Hydra to investigate Radcliffe's whereabouts. Madame Hydra shows a picture of Simmons to Fitz and insists Simmons is plotting against her. Fitz offers to send his team to eliminate her. They kiss.

Simmons and Coulson are taken to meet the leader of the Resistance: Jeffrey Mace, who introduces himself as the leader of S.H.I.E.L.D.

Mace shows Simmons and Coulson a room full of Inhuman refugees who are hiding from Hydra. May brings Daisy into a Hydra briefing where Fitz tells everyone that Simmons must be captured, dead or alive. 

Ward gives Simmons coordinates to find Radcliffe that Daisy pulled from the Hydra computers. Ward, Simmons and Coulson decide to track down Radcliffe. May's team storm Mack's house and take him and his daughter captive.

May interrogates Mack. Ward tells Simmons he'd die for Daisy. Fitz asks Madame Hydra about Simmons' true identity; Madame Hydra tells him that Simmons crossed into their world from the other side.

Madame Hydra claims that Simmons is trying to destroy the world of the Framework and tells Fitz what it was like to live in the outside world.

Daisy questions Mack. Mack tells her he remembers being a S.H.I.E.L.D. agent, before revealing that it what just something May asked him to say to trick Daisy into revealing herself. Daisy is captured by May. 

Simmons, Coulson and Ward confront Radcliffe. Radcliffe reveals that Aida killed his physical body, leaving him trapped within the Framework with Agnes. He tells Simmons that the Superior has a base in the Baltic where their friends may be located.

Madame Hydra and Fitz show up on Radcliffe's island. Madame Hydra claims that Radcliffe enslaved her in the outside world and that he's plotting to replace her with Agnes. Fitz pulls a gun on Agnes. 

Ward wants to shoot Fitz to save Agnes but Simmons begs him not to do it. Radcliffe tells Fitz about his life in the real world, including that he was in love with Simmons. Fitz doesn't believe Radcliffe and kills Agnes anyway.

Simmons screams and reveals herself to Fitz, but Ward, Simmons and Coulson manage to escape anyway. Mack is brought in by the Resistance and tells them Daisy is being held captive by Hydra. 

Fitz interrogates Daisy about her Inhuman DNA before having her dragged away. 

Agents of S.H.I.E.L.D.
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Agents of S.H.I.E.L.D. Season 4 Episode 17 Quotes

This reality may be upside down, but Fitz is still Fitz. He's a good person.

Simmons [to Daisy]

Madame Hydra: You'd really do anything for me, wouldn't you?
Fitz: I'd cross the universe for you.