Caterina Scorsone to Guest Star on Grey's Anatomy

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As predicted, an all-Shepherd crossover is in the works at Shondaland.

Grey's Anatomy's Derek (Patrick Dempsey) and Private Practice's Amelia (Caterina Scorsone) will be repairing their relationship in the upcoming season of Grey's.

Caterina, who was just promoted to series regular on Private Practice, will appear in the third episode of Grey's this season, Shonda Rhimes confirmed to TV Guide.

The premise is simple: Amelia Shepherd goes to Seattle to reconcile with her brother, Derek. The two Shepherds have not been on speaking terms since Amelia turned to drugs while grieving the death of her father, who was shot and killed in front of her and Derek.

A Solemn Derek
Caterina Scorsone Pic

Derek and Amelia will reunite this fall.

"Family is family," Scorsone says. "Regardless of the strife and tension and drama between the family members, there's a connection that is so deep. Obviously Amelia has a lot of emotion surrounding Derek and that relationship and all the things they've been through together."

In an interesting twist, Amelia will be reluctant to head to Seattle to see her brother, though she'll get a supportive push from none other than Addison (Kate Walsh) to reconcile.

"There's a lot of unresolved emotions surrounding that whole relationship. Everyone can relate to that fear of confronting situations that may result in rejection," says Scorsone.

Grey's Anatomy and Private Practice both return Thursday, September 23. What are your thoughts on the Shepherds' relationship and the upcoming crossover? Discuss!

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she'll probably be surprised to see that derek has been shot as well.

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!!!!!!!
Seems like it'll be good. (8

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Wow someone other than Addison from PrP is coming to Grey's. That the real news.

Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

I want to marry you. I want to have kids with you. I want to build us a house. I want to settle down and grow old with you. I want to die when I'm 110 years old, in your arms. I don't want 48 uninterrupted hours. I want a lifetime. Mmm. Do you see what happens? I say things like that and you fight the urge to run in the opposite direction. It's okay, I understand. I didn't, but now I do, I do. You're just getting started and I've been doing this for a long time now. Deep down, you're still an intern, and you're not ready.

Derek