19 Most Epic Grey's Anatomy Episodes: From the Pilot to the Present

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Grey's Anatomy has been a staple of our television lives for almost a decade at TV Fanatic.

Ever since its debut in the spring of 2005, Meredith Grey, Derek Shepherd and a strong cast of supporting players have occupied a special place in our hearts.

We've been through compelling cases galore, along with ups, downs, chills and thrills; shocking breakups, makeups and hookups; deaths, births and the occasional ghost visit.

Hey ... if you can bring Jeffrey Dean Morgan back, you gotta do it, by any means necessary.

Times change, cast members have come and gone, and things may not be what they once were, but even in its present form, Shonda Rhimes' creation still tugs at the heartstrings.

Here, we have picked out what we believe are the 19 most emotional, OMG-worthy and otherwise notable installments of the long-running ABC medical drama.

Scroll through and remember the most epic installments below:

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.


I couldn't agree more on "Into You like A train" being the best episode ever of Grey's Anatomy! Given there are so many to chose from, I would definitely have picked it! I would say Golden Hour was also a really good episode showing how Meredith changed as a person and a doctor through the years. Another one really close to my heart is The Becoming from season 4 with the song "Know When To Walk Away" playing.


Golden Hour from season 7 was amazing.How did it not end up here?The scene with the emergency surgery with Teddy and Meredith-was epic.Most powerful scene I have ever seen in quite a while :)


love the show.. since day one... alwys watch the reruns....
too.... never get enough especially mer.der.... all time fav. couple..they fit so well toghtr..... hpefully will not leave the show..wouldntbe the same without them.....


What about deterioration of the fight or flight response/losing my religion???
The season 2 finale was AMAZING.
Still goes down in the books as one of the best episodes of Grey's.


Grey's Anatomy Quotes

Amelia: I think I'm falling in love with Owen Hunt, and I'm really afraid that it's gonna destroy me.
Derek: It wouldn't be love if it didn't.

I want to marry you. I want to have kids with you. I want to build us a house. I want to settle down and grow old with you. I want to die when I'm 110 years old, in your arms. I don't want 48 uninterrupted hours. I want a lifetime. Mmm. Do you see what happens? I say things like that and you fight the urge to run in the opposite direction. It's okay, I understand. I didn't, but now I do, I do. You're just getting started and I've been doing this for a long time now. Deep down, you're still an intern, and you're not ready.