19 Most Epic Grey's Anatomy Episodes: From the Pilot to the Present

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Grey's Anatomy has been a staple of our television lives for almost a decade at TV Fanatic.

Ever since its debut in the spring of 2005, Meredith Grey, Derek Shepherd and a strong cast of supporting players have occupied a special place in our hearts.

We've been through compelling cases galore, along with ups, downs, chills and thrills; shocking breakups, makeups and hookups; deaths, births and the occasional ghost visit.

Hey ... if you can bring Jeffrey Dean Morgan back, you gotta do it, by any means necessary.

Times change, cast members have come and gone, and things may not be what they once were, but even in its present form, Shonda Rhimes' creation still tugs at the heartstrings.

Here, we have picked out what we believe are the 19 most emotional, OMG-worthy and otherwise notable installments of the long-running ABC medical drama.

Scroll through and remember the most epic installments below:

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.


I couldn't agree more on "Into You like A train" being the best episode ever of Grey's Anatomy! Given there are so many to chose from, I would definitely have picked it! I would say Golden Hour was also a really good episode showing how Meredith changed as a person and a doctor through the years. Another one really close to my heart is The Becoming from season 4 with the song "Know When To Walk Away" playing.


Golden Hour from season 7 was amazing.How did it not end up here?The scene with the emergency surgery with Teddy and Meredith-was epic.Most powerful scene I have ever seen in quite a while :)


love the show.. since day one... alwys watch the reruns....
too.... never get enough especially mer.der.... all time fav. couple..they fit so well toghtr..... hpefully will not leave the show..wouldntbe the same without them.....


What about deterioration of the fight or flight response/losing my religion???
The season 2 finale was AMAZING.
Still goes down in the books as one of the best episodes of Grey's.


Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

Burke was- He took something from me. He took little pieces of me, little pieces over time, so small I didn't even notice, you know? He wanted me to be something I wasn't, and I made myself into what he wanted. One day I was me Cristina Yang, and then suddenly I was lying for him, and jeopardizing my career, and agreeing to be married and wearing a ring, and being a bride. Until I was standing there in a wedding dress with no eyebrows, and I wasn't Cristina Yang anymore. And even then, I would've married him. I would have. I lost myself for a long time. And now that I'm finally me again, I can't. I love you. I love you more than I loved Burke. I love you. And that scares the crap out of me because when you asked me to ignore Teddy's page, you took a piece of me, and I let you. And that will never happen again.