No one dies on this man's watch.

That's how we always felt about Preston Burke, a brilliant heart surgeon and a kind, compassionate person. The consummate professional, and a great cook to boot. What's not to love about Dr. Burke?

Preston grew up in Alabama, where his mother owns a restaurant. He is the chief cardio-thorasic surgeon at Seattle Grace, and was long known for his grace under pressure as well as his incredible scalpel skills. Seriously, you cannot rattle the guy in the operating room or in real life.

Cristina Yang has tried during her romance with the handsome physician, which began during Season One, and which he initially broke off because of concern for his reputation.

The polar opposites then back together, however, and Cristina moved into his apartment. The evolution of their relationship despite their differences was a focal point of Grey's Anatomy for much of its second and third seasons. Preston also warmed up to Derek Shepherd, despite initial friction between the two.At the end of the second season, Preston was shot, leading to an injury that caused a tremor in his hand.

While he was healed as far as the doctors could tell, he felt pressure to return to work before he was ready. Cristina helped conceal his hand tremor, a conspiracy that ultimately boiled over and cost Burke the chance to take over for Richard Webber as Chief of Surgery.

Burke and Cristina got engaged halfway through Season Three, but at the end of the season, he left her at the altar after determining, once and for all, that she did not want to go through with it or be the person he wanted her to be. Preston has left Seattle Grace, never to return.

Preston Burke Quotes

PRESTON: "So, I have a question to ask. I checked the schedule and I noticed that both you and I are off tonight. I have a favorite restaurant. I made reservations."
CRISTINA: "None of those were questions."

PRESTON: "You're a good person."
CRISTINA: "No, I'm not."
PRESTON: "You're helping a friend."
CRISTINA: "Are his problems surgical?"
PRESTON: "No."
CRISTINA: "Then we can't help him."

Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

Lexie: [narrating] Grief may be a thing we all have in common, but it looks different on everyone.
Mark: It isn't just death we have to grieve. It's life. It's loss. It's change.
Alex: And when we wonder why it has to suck so much sometimes, has to hurt so bad. The thing we gotta try to remember is that it can turn on a dime.
Izzie: That's how you stay alive. When it hurts so much you can't breathe, that's how you survive.
Derek: By remembering that one day, somehow, impossibly, you won't feel this way. It won't hurt this much.
Bailey: Grief comes in its own time for everyone, in its own way.
Owen: So the best we can do, the best anyone can do, is try for honesty.
Meredith: The really crappy thing, the very worst part of grief is that you can't control it.
Arizona: The best we can do is try to let ourselves feel it when it comes.
Callie: And let it go when we can.
Meredith: The very worst part is that the minute you think you're past it, it starts all over again.
Cristina: And always, every time, it takes your breath away.
Meredith: There are five stages of grief. They look different on all of us, but there are always five.
Alex: Denial.
Derek: Anger.
Bailey: Bargaining.
Lexie: Depression.
Richard: Acceptance.