No one dies on this man's watch.

That's how we always felt about Preston Burke, a brilliant heart surgeon and a kind, compassionate person. The consummate professional, and a great cook to boot. What's not to love about Dr. Burke?

Preston grew up in Alabama, where his mother owns a restaurant. He is the chief cardio-thorasic surgeon at Seattle Grace, and was long known for his grace under pressure as well as his incredible scalpel skills. Seriously, you cannot rattle the guy in the operating room or in real life.

Cristina Yang has tried during her romance with the handsome physician, which began during Season One, and which he initially broke off because of concern for his reputation.

The polar opposites then back together, however, and Cristina moved into his apartment. The evolution of their relationship despite their differences was a focal point of Grey's Anatomy for much of its second and third seasons. Preston also warmed up to Derek Shepherd, despite initial friction between the two.At the end of the second season, Preston was shot, leading to an injury that caused a tremor in his hand.

While he was healed as far as the doctors could tell, he felt pressure to return to work before he was ready. Cristina helped conceal his hand tremor, a conspiracy that ultimately boiled over and cost Burke the chance to take over for Richard Webber as Chief of Surgery.

Burke and Cristina got engaged halfway through Season Three, but at the end of the season, he left her at the altar after determining, once and for all, that she did not want to go through with it or be the person he wanted her to be. Preston has left Seattle Grace, never to return.

Preston Burke Quotes

PRESTON: "So, I have a question to ask. I checked the schedule and I noticed that both you and I are off tonight. I have a favorite restaurant. I made reservations."
CRISTINA: "None of those were questions."

PRESTON: "You're a good person."
CRISTINA: "No, I'm not."
PRESTON: "You're helping a friend."
CRISTINA: "Are his problems surgical?"
PRESTON: "No."
CRISTINA: "Then we can't help him."

Grey's Anatomy Quotes

Amelia: I think I'm falling in love with Owen Hunt, and I'm really afraid that it's gonna destroy me.
Derek: It wouldn't be love if it didn't.

When we say things like "people don't change" it drives scientist crazy because change is literally the only constant in all of science. Energy. Matter. It's always changing, morphing, merging, growing, dying. It's the way people try not to change that's unnatural. The way we cling to what things were instead of letting things be what they are. The way we cling to old memories instead of forming new ones. The way we insist on believing despite every scientific indication that anything in this lifetime is permanent. Change is constant. How we experience change that's up to us. It can feel like death or it can feel like a second chance at life. If we open our fingers, loosen our grips, go with it, it can feel like pure adrenaline. Like at any moment we can have another chance at life. Like at any moment, we can be born all over again.

Meredith