CRISTINA: "I am wearing the dress. I'm ready. And, and maybe I didn't want to before. But I want to now. I really think I want this."
PRESTON: "I really wish you didn’t think. I wish that you knew."

MARK: [to Derek] "I was an excellent best man."
DEREK: [to Burke] "Worst case scenario, I sleep with your wife in 10 years."
PRESTON: [smiles]

"Cristina, I could promise to hold you, and to cherish you. I could promise to be there, in sickness and in health. I could say till death do us part. But I won't. Those vows are for optimistic couples, the ones full of hope. I do not stand here on my wedding day optimistic or full of hope. I am not optimistic. I am not hopeful. I am sure. I am steady. I'm a heart man. Take 'em apart, put 'em back together, hold them in my hands. I am a heart man. So this, I am sure. You are my partner. My lover. My very best friend. My heart. My heart beats for you. And on this day, the day of our wedding, I promise you this. I promise you to lay my heart in the palm of your hands, I promise you... me."

PRESTON: "You really don't look so good."
DEREK: "Meredith and I, we may not make it. I think I want it more than she does. But today's your day, it's all about you today."
PRESTON: "You really are a good best man."
DEREK: "I try."

PRESTON: "You okay?"
DEREK: "Fine. You need anything? Mint? A getaway car?"
PRESTON: [smiles] "If it's the Chief thing, don't worry about it. You deserve it."
DEREK: "Richard didn't pick me to be Chief."
PRESTON: "We all assumed... well, who did he pick?"
DEREK: [lying] "I don't know... wasn't me."

"I'm up there waiting for you to come down the aisle and... I know you don't want to come. If I loved you, I wouldn't be up there waiting for you. I would be letting you go."

MARK: "The bachelor party was short handed. Which explains why I'm here."
ADDISON: "I'm the only woman here. Am I supposed to the be the entertainment? Because I'm not stripping."
DEREK: "That's all right, we've all seen it before."
MARK: "True."
PRESTON: "I haven't."

PRESTON: "We have been through a lot this year."
DEREK: "And everybody else turned you down. Alright, what do I have to do?"
RICHARD: "Well, traditionally, the best man plans the bachelor party."
DEREK: "Drinks at Joe's after work."
PRESTON: "I knew you were the man for the job."

PRESTON: "Actually, Chief..."
DEREK: "You can't be his best man!"
RICHARD: "Why not?"
DEREK: "It's unethical; it's a conflict of interest. The man wants to be Chief of Surgery."
PRESTON: "Actually, Derek..."
DEREK: "Not that that's why you're asking..."
PRESTON: "I was going to ask you."
DEREK: "Ask me what? [pauses] Oh! Really?"

RICHARD: "Tomorrow's a big day."
PRESTON: "And apart from the fact that Cristina hasn't written her vows, my best man just cancelled, and it's still raining."
DEREK: "He's not ready."
RICHARD: "You're never ready. I certainly wasn't. And then, the minute I saw Adele coming down that aisle... Well. Have you picked your best man?"

RICHARD: "So, how you feeling, Preston? You ready?"
PRESTON: "Well, I'm always ready for surgery."
DEREK: "I think he's talking about the wedding."

PRESTON: "Cristina!"
CRISTINA: "Test day!"
PRESTON: "What am I supposed to tell the minister?"
CRISTINA: "Test day!"

Grey's Anatomy Quotes

When we say things like "people don't change" it drives scientist crazy because change is literally the only constant in all of science. Energy. Matter. It's always changing, morphing, merging, growing, dying. It's the way people try not to change that's unnatural. The way we cling to what things were instead of letting things be what they are. The way we cling to old memories instead of forming new ones. The way we insist on believing despite every scientific indication that anything in this lifetime is permanent. Change is constant. How we experience change that's up to us. It can feel like death or it can feel like a second chance at life. If we open our fingers, loosen our grips, go with it, it can feel like pure adrenaline. Like at any moment we can have another chance at life. Like at any moment, we can be born all over again.

Meredith

Callie: Did anyone ever think you two were a couple?
Meredith: No, because we screw boys like whores on tequila.
Cristina: Then we either try to marry them or drown ourselves.
Callie: Huh.