Meredith and Derek in a photo from the Grey's Anatomy Season 9 premiere. So sweet.
Rating: 5.0 / 5.0
This is a nice Meredith and Derek moment, isn't it? Some Grey's Anatomy fans say we don't see enough of these anymore.
Rating: 5.0 / 5.0
It's Derek vs. Meredith! These two did not end Grey's Anatomy Season 10 on a positive note.
Rating: 5.0 / 5.0
Meredith and Derek share a sexy moment in "Here Comes the Flood," the third episode from Season 5 of Grey's Anatomy. We can't wait to see their relationship evolve and grow.
Rating: 5.0 / 5.0
The only couple on this list who actually hooked up prior to the series ever starting, Grey's Anatomy kicked off the morning after Meredith and Derek went home from a bar together. Sure, he was married at the time - but that technicality was no match in the end for (sorry we have to say it...) the McDreamiest pairing on all of television.
Rating: 5.0 / 5.0
Does it get any sweeter than this? Derek holds his child as Meredith looks on.
Rating: 5.0 / 5.0
Patrick Dempsey as Derek Shepherd on Grey's Anatomy, in his new role as an instructor. How do you think he'll handle it?
Rating: 5.0 / 5.0
So handsome, always. Derek Shepherd is a very good looking man, and nothing in "Here Comes the Flood," from the fifth season of Grey's Anatomy, goes against that truth.
Rating: 5.0 / 5.0
Derek proposed to Meredith in the elevator. Appropriate, romantic and just about perfect.
Rating: 5.0 / 5.0
Derek Shepherd, seen here in "Here Comes the Flood," the third episode from Season Five of Grey's Anatomy, is the man. Any questions? Didn't think so!
Rating: 5.0 / 5.0
Derek looks on in this scene from Grey's Anatomy Season 11. It's from the episode "Can We Start Again Please?"
Rating: 5.0 / 5.0
Meredith and Derek in a photo from "Shock to the System." We have a hunch this is going to be an emotional episode.
Rating: 5.0 / 5.0

Grey's Anatomy Quotes

MEREDITH: "You don't get to call me a whore. When I met you, I thought I had found the person that I was going to spend the rest of my life with. I was done! All the boys and all the bars and all the obvious daddy issues, who cares? I was done. You left me. You chose Addison. I'm all glued back together now. I make no apologies for how I chose to repair what you broke. You don't get to call me a whore."
DEREK: "This thing with us is finished. It's over."
MEREDITH: "Finally."
DEREK: "Yeah, it's done."
MEREDITH: "It is done."

There's a reason I said I'd be happy alone. It wasn't 'cause I thought I'd be happy alone. It was because I thought if I loved someone and then it fell apart, I might not make it. It's easier to be alone, because what if you learn that you need love and you don't have it? What if you like it and lean on it? What if you shape your life around it and then it falls apart? Can you even survive that kind of pain? Losing love is like organ damage. It's like dying. The only difference is death ends. This? It could go on forever.

Meredith