Meredith and Derek in a photo from the Grey's Anatomy Season 9 premiere. So sweet.
Rating: 5.0 / 5.0
This is a nice Meredith and Derek moment, isn't it? Some Grey's Anatomy fans say we don't see enough of these anymore.
Rating: 5.0 / 5.0
It's Derek vs. Meredith! These two did not end Grey's Anatomy Season 10 on a positive note.
Rating: 5.0 / 5.0
Meredith and Derek share a sexy moment in "Here Comes the Flood," the third episode from Season 5 of Grey's Anatomy. We can't wait to see their relationship evolve and grow.
Rating: 5.0 / 5.0
The only couple on this list who actually hooked up prior to the series ever starting, Grey's Anatomy kicked off the morning after Meredith and Derek went home from a bar together. Sure, he was married at the time - but that technicality was no match in the end for (sorry we have to say it...) the McDreamiest pairing on all of television.
Rating: 5.0 / 5.0
Does it get any sweeter than this? Derek holds his child as Meredith looks on.
Rating: 5.0 / 5.0
Patrick Dempsey as Derek Shepherd on Grey's Anatomy, in his new role as an instructor. How do you think he'll handle it?
Rating: 5.0 / 5.0
So handsome, always. Derek Shepherd is a very good looking man, and nothing in "Here Comes the Flood," from the fifth season of Grey's Anatomy, goes against that truth.
Rating: 5.0 / 5.0
Derek proposed to Meredith in the elevator. Appropriate, romantic and just about perfect.
Rating: 5.0 / 5.0
Derek looks on in this scene from Grey's Anatomy Season 11. It's from the episode "Can We Start Again Please?"
Rating: 5.0 / 5.0
Derek Shepherd, seen here in "Here Comes the Flood," the third episode from Season Five of Grey's Anatomy, is the man. Any questions? Didn't think so!
Rating: 5.0 / 5.0
Meredith and Derek in a photo from "Shock to the System." We have a hunch this is going to be an emotional episode.
Rating: 5.0 / 5.0

Grey's Anatomy Quotes

[narrating] "At the end of the day, when it comes down to it, all we really want is to be close to somebody. So this thing where we all keep our distance and pretend not to care about each other, it's usually a load of bull. So we pick and choose who we want to remain close to, and once we've chosen those people, we tend to stick close by. No matter how much we hurt them. The people that are still with you at the end of the day, those are the ones worth keeping. And sure, sometimes close can be too close. But sometimes, that invasion of personal space, it can be exactly what you need."

MEREDITH

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)