Meredith and Derek in a photo from the Grey's Anatomy Season 9 premiere. So sweet.
Rating: 5.0 / 5.0
This is a nice Meredith and Derek moment, isn't it? Some Grey's Anatomy fans say we don't see enough of these anymore.
Rating: 5.0 / 5.0
It's Derek vs. Meredith! These two did not end Grey's Anatomy Season 10 on a positive note.
Rating: 5.0 / 5.0
Meredith and Derek share a sexy moment in "Here Comes the Flood," the third episode from Season 5 of Grey's Anatomy. We can't wait to see their relationship evolve and grow.
Rating: 5.0 / 5.0
The only couple on this list who actually hooked up prior to the series ever starting, Grey's Anatomy kicked off the morning after Meredith and Derek went home from a bar together. Sure, he was married at the time - but that technicality was no match in the end for (sorry we have to say it...) the McDreamiest pairing on all of television.
Rating: 5.0 / 5.0
Does it get any sweeter than this? Derek holds his child as Meredith looks on.
Rating: 5.0 / 5.0
Patrick Dempsey as Derek Shepherd on Grey's Anatomy, in his new role as an instructor. How do you think he'll handle it?
Rating: 5.0 / 5.0
So handsome, always. Derek Shepherd is a very good looking man, and nothing in "Here Comes the Flood," from the fifth season of Grey's Anatomy, goes against that truth.
Rating: 5.0 / 5.0
Derek proposed to Meredith in the elevator. Appropriate, romantic and just about perfect.
Rating: 5.0 / 5.0
Derek looks on in this scene from Grey's Anatomy Season 11. It's from the episode "Can We Start Again Please?"
Rating: 5.0 / 5.0
Derek Shepherd, seen here in "Here Comes the Flood," the third episode from Season Five of Grey's Anatomy, is the man. Any questions? Didn't think so!
Rating: 5.0 / 5.0
Meredith and Derek in a photo from "Shock to the System." We have a hunch this is going to be an emotional episode.
Rating: 5.0 / 5.0

Grey's Anatomy Quotes

Meredith: You're me.
Amelia: What?
Meredith: You're me before Derek. I can be here for you. I can do this. I get you. I can be a twisted sister for you. Just tell me how do you want to play this?

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)