Izzie has a new group of interns following her around. We will have to see how Dr. Stevens adjusts to being the one bossing peeps around instead of in the doghouse.
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Izzie and Alex used to be an item, but now they're just good friends. It's nice to see for fans of both characters.
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Rumor has it that Miranda Bailey is a little bit bitter and back to her bad-ass self in Season Four. Izzie Stevens could attest to this.
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The Season Four cast of Grey's Anatomy: Starring the lovely Ellen Pompeo (Meredith Grey), Patrick Dempsey (Derek Shepherd), Sandra Oh (Cristina Yang), Katherine Heigl (Izzie Stevens), T.R. Knight (George O’Malley), Justin Chambers (Alex Karev), Chandra Wilson (Miranda Bailey), James Pickens, Jr. (Richard Webber), Sara Ramirez (Callie Torres), Eric Dane (Mark Sloan) and Chyler Leigh (Lexie Grey).
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Izzie Stevens (Katherine Heigl) has a cow on the set of Grey's Anatomy. Almost literally. Looking on are a bunch of younger people we believe are her (!) new interns!
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Katherine Heigl, a.k.a. Izzie Stevens, is modeling her own line of scrubs! Who would have guessed?
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George couldn't even muster any words after what Izzie said to him.
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Izzie professes her feelings for George.
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Will that be enough on Cristina's wedding day?
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Alex, Cristina, Izzie and George worry about Meredith.
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Izzie loves George so much it hurts.
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Our favorite group of interns chats it up.
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Grey's Anatomy Quotes

MEREDITH: "You don't get to call me a whore. When I met you, I thought I had found the person that I was going to spend the rest of my life with. I was done! All the boys and all the bars and all the obvious daddy issues, who cares? I was done. You left me. You chose Addison. I'm all glued back together now. I make no apologies for how I chose to repair what you broke. You don't get to call me a whore."
DEREK: "This thing with us is finished. It's over."
MEREDITH: "Finally."
DEREK: "Yeah, it's done."
MEREDITH: "It is done."

You get to a point in your life when you realize you have more yesterdays than tomorrows.

Richard