It looks like that's about to happen in the Season 5 premiere of Grey's Anatomy, "Dream a Little Dream of Me," which we see a scene from here.
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At least Izzie seems to be. In the Season 5 premiere of Grey's Anatomy, "Dream a Little Dream of Me," Dr. Stevens and other doctors at Seattle Grace stand outside. What will happen next?!
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In the Season 5 premiere of Grey's Anatomy, "Dream a Little Dream of Me," five of our favorite Seattle Grace staff members stand outside. Something tells us something bad is going to happen.
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In the Season 5 premiere of Grey's Anatomy, "Dream a Little Dream of Me," four of our favorite Seattle Grace staff members stand outside their place of employment.
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In the Season 5 premiere of Grey's Anatomy, "Dream a Little Dream of Me," Izzie helps a trauma patient out of the car. Looks intense!
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Don't count on it, according to some of the Grey's Anatomy spoilers we've read.
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In this photo from the fourth season finale of Grey's Anatomy, "Freedom," Izzie is up in the face of Alex, ready to tell him how she feels. How will this end?
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In this photo from the fourth season finale of Grey's Anatomy, "Freedom," Izzie is not about to take any more crap from Alex. This Rebecca stuff has gone on long enough.
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Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

I want to marry you. I want to have kids with you. I want to build us a house. I want to settle down and grow old with you. I want to die when I'm 110 years old, in your arms. I don't want 48 uninterrupted hours. I want a lifetime. Mmm. Do you see what happens? I say things like that and you fight the urge to run in the opposite direction. It's okay, I understand. I didn't, but now I do, I do. You're just getting started and I've been doing this for a long time now. Deep down, you're still an intern, and you're not ready.

Derek