Drs. Alex Karev and Izzie Stevens, who are married, in Season 6 of Grey's Anatomy. These two make a cute couple, we've always thought - but can their marriage last?
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Izzie Stevens wigs out on Grey's Anatomy. Literally. She's got a wig on.
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Izzie cries at the grave of her deceased best friend. R.I.P., George. R.I.P.
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Alex, Izzie and Cristina cry at George's funeral. And with good reason. He meant a lot to them.
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Mr. and Mrs. Karev, Alex and Izzie, attend the funeral of Dr. George O'Malley. It is an event they are not likely to take easily.
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Izzie mourns George in the Season 6 premiere of Grey's Anatomy. It is an event that will change the lives of these doctors forever.
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Will Izzie Stevens code yet again? Or will the doctors come to her aid in the Season 6 premiere?
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Izzie Stevens and some of the new docs at Seattle Grace. Are you excited for the new blood?
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Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

When we say things like "people don't change" it drives scientist crazy because change is literally the only constant in all of science. Energy. Matter. It's always changing, morphing, merging, growing, dying. It's the way people try not to change that's unnatural. The way we cling to what things were instead of letting things be what they are. The way we cling to old memories instead of forming new ones. The way we insist on believing despite every scientific indication that anything in this lifetime is permanent. Change is constant. How we experience change that's up to us. It can feel like death or it can feel like a second chance at life. If we open our fingers, loosen our grips, go with it, it can feel like pure adrenaline. Like at any moment we can have another chance at life. Like at any moment, we can be born all over again.

Meredith