Izzie, Alex and Cristina at George's funeral. We will see this unfold when the new season of Grey's Anatomy airs.
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Alex reacts as Izzie slips away from him, possibly for the last time.
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Is Izzie about to slip away into the afterlife?
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Alex calls for help as Izzie fades into unconsciousness.
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Cristina and Izzie share a moment in "Now or Never."
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Izzie Stevens crashes at the end of "Now or Never." Will she live?
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Alex and Izzie don't know what the best course of action is going forward, and it's hard to blame them.
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Izzie and Alex embrace in the fifth season finale.
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Izzie Stevens may be bald, but she's still hot in the eyes of Alex Karev, and all of us.
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Meredith tries to help Izzie remember images while Derek runs tests.
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Has Izzie Stevens passed away? If that is what we are supposed to take away from the powerful scene at the end, it was certainly emotionally devastating, but great television.
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Alex tends to ailing Izzie in an emotional Season Five scene from Grey's Anatomy. These two have become bigger and bigger characters since the series debuted.
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Grey's Anatomy Quotes

MEREDITH: "You don't get to call me a whore. When I met you, I thought I had found the person that I was going to spend the rest of my life with. I was done! All the boys and all the bars and all the obvious daddy issues, who cares? I was done. You left me. You chose Addison. I'm all glued back together now. I make no apologies for how I chose to repair what you broke. You don't get to call me a whore."
DEREK: "This thing with us is finished. It's over."
MEREDITH: "Finally."
DEREK: "Yeah, it's done."
MEREDITH: "It is done."

You get to a point in your life when you realize you have more yesterdays than tomorrows.

Richard