In this photo from "Losing My Mind," Derek Shepherd (Patrick Dempsey) and Meredith Grey (Ellen Pompeo) work with patients... and work with each other!

In this photo from "Losing My Mind," Derek Shepherd (Patrick Dempsey) looks as handsome as ever. He needs to get his act together and propose to Meredith!

In this photo from "Losing My Mind," Meredith and Derek share smiles. It's just a matter of time before they are together for good!

In this photo from "Losing My Mind," Derek Shepherd is hard at work. Maybe he needs to work a little harder with Meredith, too!

In this photo from "Losing My Mind," Meredith and Derek are hard at work on their clinical trial. Will this be what brings them back together?

We'll stand by you, Mer, as you get over your issues. But can you hurry it up a little?

Ellen Pompeo was seen working out in L.A. in April 2008. She's so cute.

To us, it doesn't get better than Ellen Pompeo. This Grey's Anatomy star lights up the screen as Meredith Grey and is one of our favorite celebs in real life.

A nice photo of Justin Chambers and Keisha Chambers, who have been married nearly a decade and a half. Amazing in this day and age!

In this photo from "Piece of My Heart," Dr. Mark Sloan (Eric Dane) enjoys a smile at the expense of his friend Derek Shepherd, who's surrounded by all sorts of women he has complicated histories with.

In this photo from "Piece of My Heart," Addison looks on as Rose (Lauren Stamile) watches the floors tick by, wishing she could just get off the elevator. Fans probably want her off it as well ... and falling down the elevator shaft!

In this photo from "Piece of My Heart," Dr. Derek Shepherd (Patrick Dempsey) may be having the elevator ride from hell, but man, he's still so handsome. Love him!