Will trouble hit Derek Shepherd in the Grey's Anatomy Season Six finale May 20? What can he do to avoid it, if anything?
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What happens with April in the Grey's Anatomy season finale? That's what a lot of fans have been wondering.
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A photo of Callie from the Season 6 finale of Grey's Anatomy. This woman has endeared herself to us over the course of four-plus seasons now.
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Callie and Arizona in the sixth season finale of Grey's Anatomy. These two rock, there's no other way to put it!
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We love Arizona. How can you not? We hope she and Callie can patch things up.
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Arizona and Callie work their magic in the Grey's Anatomy season finale. We just hope it's enough for an ailing patient.
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The surgical team at Seattle Grace is going to be put to the test. This week perhaps more than ever before.
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Callie and Arizona in the Grey's Anatomy Season Six finale. They're seen here wheeling in a patient.
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Derek in the Season 6 finale of Grey's Anatomy. Will this season end on a catastrophic note for one or more characters?
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Mandy Moore guest stars on the Grey's Anatomy season finale. Will her character meet a disastrous end?
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Will the Grey's Anatomy staff be able to help a teenage patient, played by guest star Demi Lovato, who has serious brain issues? Here's hoping they can.
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Alex and his patient's parents look in "Shiny, Happy People." He's the man, but he may be up against in this time.
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Grey's Anatomy Season 6 Quotes

Lexie: [narrating] Grief may be a thing we all have in common, but it looks different on everyone.
Mark: It isn't just death we have to grieve. It's life. It's loss. It's change.
Alex: And when we wonder why it has to suck so much sometimes, has to hurt so bad. The thing we gotta try to remember is that it can turn on a dime.
Izzie: That's how you stay alive. When it hurts so much you can't breathe, that's how you survive.
Derek: By remembering that one day, somehow, impossibly, you won't feel this way. It won't hurt this much.
Bailey: Grief comes in its own time for everyone, in its own way.
Owen: So the best we can do, the best anyone can do, is try for honesty.
Meredith: The really crappy thing, the very worst part of grief is that you can't control it.
Arizona: The best we can do is try to let ourselves feel it when it comes.
Callie: And let it go when we can.
Meredith: The very worst part is that the minute you think you're past it, it starts all over again.
Cristina: And always, every time, it takes your breath away.
Meredith: There are five stages of grief. They look different on all of us, but there are always five.
Alex: Denial.
Derek: Anger.
Bailey: Bargaining.
Lexie: Depression.
Richard: Acceptance.

Burke was- He took something from me. He took little pieces of me, little pieces over time, so small I didn't even notice, you know? He wanted me to be something I wasn't, and I made myself into what he wanted. One day I was me Cristina Yang, and then suddenly I was lying for him, and jeopardizing my career, and agreeing to be married and wearing a ring, and being a bride. Until I was standing there in a wedding dress with no eyebrows, and I wasn't Cristina Yang anymore. And even then, I would've married him. I would have. I lost myself for a long time. And now that I'm finally me again, I can't. I love you. I love you more than I loved Burke. I love you. And that scares the crap out of me because when you asked me to ignore Teddy's page, you took a piece of me, and I let you. And that will never happen again.

Cristina