Foreman, House and Thirteen observe as a patient undergoes a highly experimental surgery. That's pretty much the status quo each week.
Added:
Does House look more tired than usual? He hasn't slept in days during this scene from "Under My Skin."
Added:
House is having major sleep issues in the episode "Under My Skin." Cuddy to the rescue!
Added:
Cuddy tries to help House fall asleep. We have a few idea of how she could accomplish this.
Added:
In "Under My Skin," Wilson examined his BFF. House is having a lot of trouble sleeping.
Added:
As House's fifth season winds down, the doctor has more and more trouble sleeping. Visions of Amber will do that to anyone.
Added:

House Season 5 Episode 23 Quotes

So, you're saying... you want a prenup. In liquid form.

Dr. Chase (to Cameron)

Dr. Wilson: The door was closed for a reason.
House: Well, now it's opened for a reason. We need to talk.
Patient: He just told me I have kidney cancer.
House: Then you obviously need a moment to process.