This is a photo from The Good Samaritan Killer. It was episode 11 of The Blacklist.
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Red is on the hunt for the person who betrayed him on The Blacklist. "The Good Samaritan Killer" is the 11th episode of the show's first season.
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The Blacklist Season 1 Episode 11 Quotes

Don't look so stricken. The first shot will kill you.

Red

Janice, if you don’t stop yammering, I’m going to have to shoot through this door.

Red