Mrs Krabappel gets a little drunk when Bart spikes her coffee in the latest episode of The Simpsons, "Bart Gets a Z." Unfortunately this also gets her fired.
Added:

The Simpsons Season 21 Episode 2 Quotes

How could Mrs. Krabappel take my cell phone? I'm only on month one of a sixty month plan

Milhouse

Nelson [about the school's ancient computer]: My stroked out grandfather has more memory tha that thing
Milhouse: How's he doing?
Nelson: Better, thanks