Rebecca: He was the closest thing I'll ever have to a son. The closest thing I'll ever have to sharing my blood.
Aidan: I'm sorry.

Carla: That nurse makes me feel so old.
Dr. Kelso: Oh, calm down, nurse Espinosa. I have it on good authority that she's a dude.
Carla: I made that stuff up.
Dr. Kelso: Then it's time for her to meet Bob Kelso, licensed hetero.

You need something to distract from your horrible personality. Most of the time, I can't stand to be in the same room as you.

Kurt

I'm pleased to announce that the National Earth Day Organization has chosen South Park as its location for the Earth Day Brainwashing Festival!

Ms.Choksondick

Trust is hard for surgeons. We're trained from day one to believe that the only person we can trust is ourselves.

Derek

Joanna: Billy, what if there's a little David Hanley growing inside me?
Billy: It's not possible. You won't let that happen.

I loved being you. Every second of it. Oh, the way you burned like a sun, like a whole screaming world on fire. I remember that feeling. And I always will. And I will always miss it.

Missy

No hero can save everyone, not even Superman. But a real hero never stops trying.

James

Teddy: Come on, Evelyn, give the kid a break. He was probably out last night sowing some wild oats.
Evelyn: He's 40 years old! He has no more wild oats. Just warmed over Cream of Wheat.

Smithers: I'm so happy I could hug you.
Mr. Burns: And have me smell like cheap drug store cologne the rest of the day? You may hug my shadow.

I hate traffic, the band and the phenomenon.

Homer

Martin: Malcolm, you really should respect your mother's ... Ainsley!
Ainsley: Dr. Whitley, it's been a long time.
Martin: It has, but please, call me dad.