It's all supposed to be with you. I thought you got that. I didn't think I needed to say it. So when I say I can't say no to my friend, it doesn't mean I'm saying no to you.

Meredith: I hurt her feelings, and she's mad at me. I forgot I'm supposed to be her sister.
Alex: You're a complete tool sometimes.
Meredith: I've heard.

There ought to be some rule, you know? People who have been in a plane crash can't work on one.

You want to be a mess, be a mess. I don't care. I can take it.

Callie: You [Meredith] and Derek are living proof that love exists. That it works, that there is hope. You guys are a freaking romance novel, and I, for one, am rooting for you two. Team MerDer!
Alex: I'm not saying that.

Meredith: She was perky, and she sounded happy and tall with a lot of great hair.
Alex: You saw her? How did you see her?
Meredith: I didn't. I heard her voice. Her perky, happy, tall voice.
Maggie: I hate voices like that.
Alex: You can tell by the voice?

Alex: The fact that you were checking your texts while you were doing it is already sad.
Meredith: We have a special ring tone. Hey you want a special ring tone?
Alex: No.

You're a really good mom. You've been riding me all day, making sure I don't screw up. Crap, you've been doing it all these years. It sucks. It's annoying, but it's nice.

Look at me. You got me. I'm not going anywhere except home with you.

It’s just us now.

Dude, you’re being weird. Get out of my car before you escalate.

Arizona: What’s wrong with your face?
Alex: I like your hair.
Arizona: What did you do?

Grey's Anatomy Quotes

When we say things like "people don't change" it drives scientist crazy because change is literally the only constant in all of science. Energy. Matter. It's always changing, morphing, merging, growing, dying. It's the way people try not to change that's unnatural. The way we cling to what things were instead of letting things be what they are. The way we cling to old memories instead of forming new ones. The way we insist on believing despite every scientific indication that anything in this lifetime is permanent. Change is constant. How we experience change that's up to us. It can feel like death or it can feel like a second chance at life. If we open our fingers, loosen our grips, go with it, it can feel like pure adrenaline. Like at any moment we can have another chance at life. Like at any moment, we can be born all over again.

Meredith

Callie: Did anyone ever think you two were a couple?
Meredith: No, because we screw boys like whores on tequila.
Cristina: Then we either try to marry them or drown ourselves.
Callie: Huh.