You should wear your hair up more. Shows off the back of your neck. I like the back of your neck.

Owen (to Cristina)

Callie: You're an idiot. What is your problem?
Mark: He is proposing to her. That makes Little Her, his little sister. And I can't sleep with any more sisters. And she's young. And I'm her boss.
Callie: And I'm celibate.

Lexie: You're the only one who knows about us and I'm terrible at keeping secrets. Keeping secrets makes me sick.
Callie: Look. Alone people don't like to hear about the together people. Okay. Even if the alone people are alone by choice. It's just sort of mean. It's sort of like bringing a 6-pack to an AA meeting.

Lexie (talking about Mark): He's fun and he's funny. Even with no sex we just laugh and we talk.
Callie: Yeah. I don't want to hear this.

Callie (to Owen): Can you do it?
Mark: Him? No. He's a meatballer.
Callie: He is meticulous and he will keep his mouth shut.
Owen: I've done operations like this before. It's not that complicated.
Mark: Guys run into this problem on the battlefield, do they?
Owen: I don't think you and I should talk about how guys run into this.

Mark: Pain and agony for a little bit of pleasure? I get it.
Callie: If it's that bad, why don't you stop sl- ... doing what you're doing.
Mark: Because it doesn't feel bad when I'm ... doing it. It's good. It's great. And maybe if you weren't so scared of getting burned, you'd feel the same.

Mark: I'm telling you, these interns are out of control.
Callie: Stalkers.
Mark: Sexed-up stalkers.

Mark: We're going to need a strategy. Their hot little eyes tracking our every move.
Callie: Okay. No casual glances over the shoulder. No "this is interesting, come and have a see."

Mark: We did good work today.
Callie: If we stay strong...
Mark: Don't get drunk...
Callie: Keep staring at Joe, we'll be fine.

Mark: Did she, uh, she say goodbye to you?
Callie: No.
Mark: You okay?
Callie: Do I look okay?
Mark: You look great.
Callie: Then I'm okay.

Cristina: Wait, so are you a lesbian now?
Mark: I dunno... maybe you were a "once-bian."
Callie: Or a twice-bian. Whatever. It's over.
Cristina: Are you okay?
Mark: She's fine. Leave her alone.

Callie: We had a fight.
Cristina: Please. Meredith and I fight all the time. We still work together. It's not like Hahn was your girlfriend or something. [long pause] Oh my God. She was your girlfriend?
Callie: We hadn't figured it all out.

Grey's Anatomy Quotes

When we say things like "people don't change" it drives scientist crazy because change is literally the only constant in all of science. Energy. Matter. It's always changing, morphing, merging, growing, dying. It's the way people try not to change that's unnatural. The way we cling to what things were instead of letting things be what they are. The way we cling to old memories instead of forming new ones. The way we insist on believing despite every scientific indication that anything in this lifetime is permanent. Change is constant. How we experience change that's up to us. It can feel like death or it can feel like a second chance at life. If we open our fingers, loosen our grips, go with it, it can feel like pure adrenaline. Like at any moment we can have another chance at life. Like at any moment, we can be born all over again.

Meredith

Callie: Did anyone ever think you two were a couple?
Meredith: No, because we screw boys like whores on tequila.
Cristina: Then we either try to marry them or drown ourselves.
Callie: Huh.