CRISTINA: "There's a club. The Dead Dads Club. And you can't be in it until you're in it. You can try to understand, you can sympathize. But until you feel that loss... My dad died when I was nine. George, I'm really sorry you had to join the club."
GEORGE: "I... I don't know how to exist in a world where my dad doesn't."
CRISTINA: "Yeah, that never really changes."

Cristina: I have five rules. Memorize them. Rule number one, don't bother sucking up. I already hate you, that's not gonna change.
Izzie: Traumas protocol, phone lists, pagers. The nurses will page you, you answer every page at a run. A RUN! That's rule number two... You're supposed to follow me!
Alex: The first shift starts now and lasts 36 hours. You're grunts, nobodies, the bottom of the surgical food chain. You run labs, write orders, work every second night until you drop. And you don't complain.
Meredith: On call rooms. Sleep when you can, where you can. You know, but not with anybody. Not attendings, especially not attendings. Sleeping with attendings, not a good idea. Where was I?
George: Er, rule number three. If you're sleeping, do not wake you unless the patient is actually dying.
Cristina: The dying patient better not be dead when I get there, because not only will you have killed someone, you will have woken me for no good reason. Are we clear? Yes?
Lexie: That was four rules. You said five.
Cristina: Rule number five. When I move, you move... Go!

IZZIE: [to Alex] "We're all pulling for you."
GEORGE: "We are?"

GEORGE: [helping Alex practice] "Aw, my throat! It's like, wicked soar, yo. Plus I got, like, all deez sick breakouts!"
IZZIE: "You're helping him!?" [storms off]
GEORGE: [to Alex] "I was doing mono. The whole acne thing was just being a teenager."

IZZIE: "Morning."
GEORGE: "I thought we were all done with the whole muffin thing."
IZZIE: "This isn't muffins. This is breakfast."
MEREDITH: "Are you okay?"
IZZIE: "Of course I'm okay. I'm a millionaire."

MEREDITH: [to Derek] "I am a sink with an open drain, and anything you say runs straight out." [storms off]
GEORGE: "She probably could have used a better metaphor."
IZZIE: "Give her a break, she's got a hangover."

MIRANDA: "How many valve replacements have you performed in your life, Dr. O'Malley?"
GEORGE: "None."
MIRANDA: "None! And how many valve replacements do you think Dr. Hahn has performed?"
GEORGE: "That is my father!"
MIRANDA: "You're in that room as his son! You interns think you can do whatever you wanna do. Not anymore! Not with me! Which is why you are going to stay away! 50 feet away to be precise! You are going to remain 50 feet away from your father at all times today! And Dr. O'Malley, do not make me tell you again."

[enraged, tackling Alex] "You gave me syphilis!?"

MEREDITH: "Free time sucks."
GEORGE: "When would have been a good time to hear about your boyfriend's wife?"
MEREDITH: "Are you mad at me or something?"

GEORGE: "What happened today?"
IZZIE: "Nothing."
MEREDITH: "Nothing."
GEORGE: "Okay then."
IZZIE: "We don’t know everything about each other, George."
GEORGE: [pause] "True. Anybody wanna have sex?"

RICHARD: "People! I know who did this, so you might as well come clean. I know!"
GEORGE: "With all due respect, sir, if you knew you wouldn't be asking us."
IZZIE: "I did it."
MEREDITH: "You have your suspicions, but you don't actually know."
CRISTINA: "Not for sure."
GEORGE: "And you can't do anything to any of us without proof, sir."

[to his dad] "That neighbor kid, Mike Wildon, I did hit in the face with a stick. Um.. when his dad came over and was yelling and you asked me if it was true... I lied. And you thought I never lied. So you took my side, and you and his dad got in that big fight. And then his kids egged our house. Then Ronny and Jerry went over and blew up his lawnmower. Anyway. I did it. He was teasing me, and he was bigger than me. So I hit him with a stick to reach his face. And I lied to you dad. So, I'm saying I'm sorry. [pause] Dad? [pause] If you have any more fight in you, if you could fight this thing just... just a little harder that would be good. Then you could come home."

Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

MEREDITH: "You don't get to call me a whore. When I met you, I thought I had found the person that I was going to spend the rest of my life with. I was done! All the boys and all the bars and all the obvious daddy issues, who cares? I was done. You left me. You chose Addison. I'm all glued back together now. I make no apologies for how I chose to repair what you broke. You don't get to call me a whore."
DEREK: "This thing with us is finished. It's over."
MEREDITH: "Finally."
DEREK: "Yeah, it's done."
MEREDITH: "It is done."