CRISTINA: "There's a club. The Dead Dads Club. And you can't be in it until you're in it. You can try to understand, you can sympathize. But until you feel that loss... My dad died when I was nine. George, I'm really sorry you had to join the club."
GEORGE: "I... I don't know how to exist in a world where my dad doesn't."
CRISTINA: "Yeah, that never really changes."

Cristina: I have five rules. Memorize them. Rule number one, don't bother sucking up. I already hate you, that's not gonna change.
Izzie: Traumas protocol, phone lists, pagers. The nurses will page you, you answer every page at a run. A RUN! That's rule number two... You're supposed to follow me!
Alex: The first shift starts now and lasts 36 hours. You're grunts, nobodies, the bottom of the surgical food chain. You run labs, write orders, work every second night until you drop. And you don't complain.
Meredith: On call rooms. Sleep when you can, where you can. You know, but not with anybody. Not attendings, especially not attendings. Sleeping with attendings, not a good idea. Where was I?
George: Er, rule number three. If you're sleeping, do not wake you unless the patient is actually dying.
Cristina: The dying patient better not be dead when I get there, because not only will you have killed someone, you will have woken me for no good reason. Are we clear? Yes?
Lexie: That was four rules. You said five.
Cristina: Rule number five. When I move, you move... Go!

[last lines] "I love you too."

CRISTINA: "Meredith's a WASP, isn't she? Liquor is like oxygen for WASPs."
GEORGE: Which is... probably why we're out of liquor."

IZZIE: "You don't have to do this. You don't have to transfer to Mercy West."
GEORGE: "Yeah, I do."

[to himself] "This is George, George has a hot date."

IZZIE: "I don’t know how we do this. I don’t know how we work together and be friends and act like it’s all okay."
GEORGE: "I... there’s a spot available at Mercy West. I called them."
IZZIE: "You’re gonna transfer to Mercy West?"
GEORGE: "I have to."

[the cast, narrating]
MEREDITH: "Human beings need a lot of things to feel alive."
GEORGE: "Family"
IZZIE: "Sex"
DEREK: "But we only need one thing"
RICHARD: "To actually be alive."
CRISTINA: "We need a beating heart."
ADDISON: "When our heart is threatened"
ALEX: "We respond in one of two ways."
GEORGE: "We either run or-"
IZZIE: "We attack."
RICHARD: "There's a scientific term for this."
ALEX: "Fight..."
ADDISON: "...or flight."
MIRANDA: "It's instinct."
MEREDITH: "We can't control it."
IZZIE: "Or can we?"

PRESTON: "How are you and uh, Dr. Torres doing these days?"
GEORGE: "Good. She doesn't know it yet, but we are. We... Excellent really. For a while, uh, she wanted, uh, a certain level of commitment, and I just didn't feel that way. I was ri- Now I am though."
PRESTON: "So you're stepping up."
GEORGE: "I am stepping up. You knew right? It was the right time. With you and Christina?"
PRESTON: "Right."

PRESTON: "How's your father O'Malley, anything new?"
GEORGE: "He needs an endoscopy, and Bailey won't let me be the intern on his case. But she said I could pick someone else, and I was wondering if Cristina could be the intern on his case."
PRESTON: "That shouldn't be a problem."
CRISTINA: "Uh, yes it is! We have corartendoctonectomy scheduled at noon."
PRESTON: "I'll push it, O'Malley's father deserves the best!"

RICHARD: "People! I know who did this, so you might as well come clean. I know!"
GEORGE: "With all due respect, sir, if you knew you wouldn't be asking us."
IZZIE: "I did it."
MEREDITH: "You have your suspicions, but you don't actually know."
CRISTINA: "Not for sure."
GEORGE: "And you can't do anything to any of us without proof, sir."

George: Did you know how to do the procedure?
Richard: Are you saying that we're too old to learn the new ways, O'Malley?
George: No.
Richard: Are you saying we're old dogs who can't learn the tricks?
George: No. I just...
Mark: We're not old dogs.
Webber: We still got it.

Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

There's a reason I said I'd be happy alone. It wasn't 'cause I thought I'd be happy alone. It was because I thought if I loved someone and then it fell apart, I might not make it. It's easier to be alone, because what if you learn that you need love and you don't have it? What if you like it and lean on it? What if you shape your life around it and then it falls apart? Can you even survive that kind of pain? Losing love is like organ damage. It's like dying. The only difference is death ends. This? It could go on forever.