IZZIE: "You want us to make her seize? How do we make someone have a seizure?"
DEREK: "Get creative. Do some research."
GEORGE: "Well, if all the normal methods have failed then what are we supposed to do-"
DEREK: "Use a strobe light. Get her drunk. Hang her up upside down from the ceiling and hit her with a wiffle ball bat, for all I care. Just make her seize. 'Cause until she seizes, I don't know when to operate, and if I don't know when to operate, I can't get this woman out of my life. And this woman is not how I like to start my mornings."

MR. HUMPHREY: [holding up magazine] "You don't need to do anything. Is this you? Is this you? It is, isn't it? You know what... go. Just... get out of my room."
IZZIE: "Mr. Humphrey-"
MR. HUMPHREY: "Get out of my room!"

Penmanship saves lives!

Alex: Dude, he is fried.
Meredith: He is not fried. He lost a patient, and got hit with a law suit all in one week. He just needs time.
Alex: He's been sitting there for 3 days. The sofa cushions are gonna start bonding to his ass, and he's eating all my cereal.
Izzie: He's taking stock. Something huge and life altering happened to him and he's taking stock. Figuring out his next move. We shouldn't judge him, we shouldn't rush him.
Alex: Whatever. Sylvia Plath's picking out all the marshmallows. Their the best part!
Lexie: And I'm pretty sure he's sitting on my keys. I'd ask him to move, but he looks so comfy.
Meredith: You guys are cowards!

IZZIE: "George, can I come in? I made you some cookies and brownies and muffins, of course. I always make muffins."
CALLIE: [runs out the door] "Thank God you're here. I can't take it anymore. Three times already tonight, and he's getting ready for a fourth."
IZZIE: "What are you talking about? Oh. Oh, ew."

Swinder: The test impaired your memory to such a degree that I have to strongly recommend that you don't have the surgery.
Derek: Izzie, the test was the worst case scenario. The result has nothing to do with the surgery.
Swinder: We don't know that.
Derek: But what I do know is that not operating is every bit as risky as the surgery itself. If not more. But, it's up to you.
Izzie: What do you think?
Alex: I think he's talking to you, not me.
Derek: I'll leave you two alone to discuss this.
Alex: Ah, I'll come with you. I have a couple of questions.
Izzie: Wait, Alex.
Alex: Think about what you want to do for a second, ok? I'll be right back.
(everyone but Mer leaves the room. Mer closes the door)
Meredith: You are not having the surgery!

ADDISON: "Did you know about the slutty sex your slutty friend had with my super slutty husband?"
IZZIE: "You should have a muffin. They're really good and they help you."
ADDISON: "I may be beyond help."
IZZIE: [walks out] "Yeah, me too. Don't let her drive Joe."
ADDISON: [eats a muffin] "Mmm. Good!"

Izzie: Whatcha reading?
Alex: I have this patient I'm trying to diagnose. It's driving me nuts.
Izzie: So take a break, I miss you.
Alex: I'm right here.
Izzie: No you're not. You're here, but you're not here. And I miss you.
Alex: Iz, come on. I'm trying to work.
Izzie: I'm wishing for a brain tumor. I'm wishing all the time for a giant tumor that would just press down on my brain and make me hallucinate George. So that I could talk to him again, so I could laugh with him again. I miss him so much. I miss him all the time, and I just want to feel better. Even for a minute you know, I just want to be a person who isn't wishing for a brain tumor. Just for one minute. And, I can't drink because of the cancer meds, I don't do drugs, I can't even work right now. I don't have any distractions. I'm sad, and I miss George. So please, please, come inside and help me feel better.
Alex: "I miss George". Nice. Real seductive.

"You think... you think you know someone, know who they are. You share a house and make wishes on eyelashes with them and we don't know each other, none of us. We're just a bunch of interns who work together. There's nothing there!"

MEREDITH: "Talk about divine retribution."
IZZIE: "What?"
MEREDITH: "He sleeps with his assistant, a carnivorous fish lodges itself in his penis, that's instant karma if I've ever seen it."
CRISTINA: "Well, Derek wasn't struck by lightning and neither were you."
MEREDITH: "Addison showed up, I had months of pain and self-loathing, crazy ranting mother and near drowning off the side of the dock, I mean, it's no fish in my ho-ho, but it's certainly not an easy ride."
CRISTINA: "Well, you know, I cheated on my boyfriends and I'm fine. I mean, am I the only one?"

IZZIE: "Do you mind me asking why you guys switched from Dr. Burke to Dr. Hahn?"
MR. O'MALLEY: "No, we didn't. Georgie did."
IZZIE: "Did he say why?"
MR. O'MALLEY: "Not really, no."
MRS. O'MALLEY: "Did George and Dr. Burke maybe have a falling out?"
IZZIE: "Not that I know of."

Izzie: I'm sorry ... I can't.
Denny: It's okay. I'll be right here.

Grey's Anatomy Quotes

[walking by Izzie's room]
Meredith: Hot.
Sadie: Horny.

Sexual sorbet? Hahaha! I love it.

Bailey