Lexie: [narrating] Grief may be a thing we all have in common, but it looks different on everyone.
Mark: It isn't just death we have to grieve. It's life. It's loss. It's change.
Alex: And when we wonder why it has to suck so much sometimes, has to hurt so bad. The thing we gotta try to remember is that it can turn on a dime.
Izzie: That's how you stay alive. When it hurts so much you can't breathe, that's how you survive.
Derek: By remembering that one day, somehow, impossibly, you won't feel this way. It won't hurt this much.
Bailey: Grief comes in its own time for everyone, in its own way.
Owen: So the best we can do, the best anyone can do, is try for honesty.
Meredith: The really crappy thing, the very worst part of grief is that you can't control it.
Arizona: The best we can do is try to let ourselves feel it when it comes.
Callie: And let it go when we can.
Meredith: The very worst part is that the minute you think you're past it, it starts all over again.
Cristina: And always, every time, it takes your breath away.
Meredith: There are five stages of grief. They look different on all of us, but there are always five.
Alex: Denial.
Derek: Anger.
Bailey: Bargaining.
Lexie: Depression.
Richard: Acceptance.

"People die in front of us everyday. But I believe Meredith will survive this. I believe, I believe, I... I believe in the good. I believe that it's been a hell of a year and I believe that, in the face of overwhelming evidence to the contrary, that we will be okay. I believe a lot of things. I believe that... I believe that Denny is always with me... and I believe that if I eat a tub of butter and no one sees, that the calories don't count. And I believe that surgeons who prefer staples over stitches are just lazy. And I believe that you are a man that made a terrible mistake marrying Callie and I believe that because I'm your best friend I can tell you this and we can be okay. I believe that even though you made this mistake you will be okay. I believe we survive, George. I believe that believing we survive... is what makes us survive."

IZZIE: "I'm a pretty girl."
RICHARD: "What?"
IZZIE: "I'm not being arrogant, it's just, it's just kind of a fact. For a long time I made a career from my looks, so I get it, I'm a pretty girl. And not in a 'from a certain angle' way, in an obvious way. It’s the blonde thing and the big boobs thing. Big boobs are a key to 'obvious pretty' if you know what I'm saying."
RICHARD: "Dr. Stevens-"
IZZIE: "It's how men see me. I'm not a smart girl or an interesting girl, I'm a pretty girl. The blonde and the boobs, it confuses guys into thinking I'm someone else. And I'm used to it. And I'm used to them walking away when they realize… But then Denny goes and asks me to marry him."
RICHARD: "Is that why you cut the wires?"
IZZIE: "He doesn't make me feel like I'm a pretty girl. He makes me feel like… like me. I think he might know me. And so, if I did cut the LVAT wire, and I'm not saying that I did, but if I did, then no. I don't feel guilty. I know that I should. I would if it were anybody else's. But I can't feel anything but happy."

Izzie: You never know the biggest day of your life is the biggest day. Not until it's happening. You don't recognize the biggest day of your life, not until you're right in the middle of it. The day you commit to something or someone. The day you get your heart broken. The day you meet your soul mate. The day you realize there's not enough time, because you wanna live forever. Those are the biggest days. The perfect days. You know?
Denny: I bet you ... you made a beautiful bride.
Izzie: It was a beautiful day.
Alex: You put the scarf on. I told you, you don't need it. You look gorgeous without it.
Denny: He's right.
Izzie: Go away now. Go away, I wanna be alone with my husband.
Alex: (Takes off her scarf, and kisses her forehead) My wife is hot!
(Izzie giggles and smiles)

Izzie: They tried number 9? Who does 9?
Sadie: Well personally I'm a fan of 5, 7, 8, pretty much 12 through 20.
Meredith (laughs): I would try 15.
Izzie: Don't. Don't try 15. I would try 16. Yeah. I've never done that before.
Alex: You'd try 16?
Izzie: Uh huh. I would. I totally would. (Izzie and Alex look at each other then quickly leave the table)
Lexie: Um, don't do 16 too fast. It can hurt badly ... I heard.

Swinder: You wanna remove her hippocampus?
Derek: One of them. It's a common procedure for seizure patients
Swinder: Moving her hippocampus could compromise her memory, her speech, she wouldn't be able to practice medicine anymore.
Derek: I have performed this surgery hundreds of times.
Swinder: On cancer patients?
Derek: No. But it's...
Izzie: If you do the surgery I could lose my memory?
Derek: It's unlikely but it's possible.
Izzie: And, if you don't do the surgery...
Swinder: We could shrink the tumor with IL2.
Izzie: If the tumor doesn't kill me first.
Derek: Why take the chance?
Swinder: Have you even done a WADA test to see how her memory would be affected?
Derek: Putting her brain to sleep and asking her to remember a bunch of flash cards is not an accurate assessment of the post surgical outcome.
Swinder: But, it would tell us whether or not she could function afterwards. And, as Dr. Stevens primary physician...
Derek: Fine I'll do it. It's unnecessary but...
Swinder: The surgery is unnecessary.
Derek: The tumor is already symptomatic, she's having hallucinations.

George: Did you only shave one leg?
Izzie: (starts crying) I know, I'm sorry!!!

Izzie: What are you doing in here?
Derek: I was thinking about making this my office when you move out.
Izzie: When I move out? When am I moving out?
Derek: Oh. Soon?

[to Alex] "Was it me? We seemed to be having a normal time."

Alex: Chicken.
George: Good chicken.
Meredith, Cristina: It's chicken.
Izzie: I know it's chicken! I wanna know what it tastes like.
Alex: Tastes like chicken.
Izzie: I'm having surgery today.
Bailey: Maybe, if the meds are strong.
Izzie: I am maybe having surgery today, and as such I cannot taste the chicken for myself. So I really need you guys to tell me what it tastes like. I need to nail down this dinner, so I can announce it on Meredith and Derek's wedding website.
Meredith: There's a website?
Izzie: So, can you please be a little more articulate than just chicken?

IZZIE: [to Alex] "You are hateful! Hateful! Hateful, arrogant, lazy... hateful man! Hateful!"
DEREK: "Well, never a dull moment here at Seattle Grace. Scalpel?"

GEORGE: "We have to do something. Meredith has become like an exhibit. Like a zoo animal. Like that rare panda that everyone stares at."
IZZIE: "Please don't say that to her face. I think that panda died alone."
GEORGE: "I'm just saying we should do something to cheer her up."
CRISTINA: "I've got something."

Grey's Anatomy Quotes

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)

There's a reason I said I'd be happy alone. It wasn't 'cause I thought I'd be happy alone. It was because I thought if I loved someone and then it fell apart, I might not make it. It's easier to be alone, because what if you learn that you need love and you don't have it? What if you like it and lean on it? What if you shape your life around it and then it falls apart? Can you even survive that kind of pain? Losing love is like organ damage. It's like dying. The only difference is death ends. This? It could go on forever.