Sheldon: I'm a physicist. I have a working knowledge of the entire universe and everything it contains
Penny: Who's Radiohead?
Sheldon [after twitching for a minute]: I have a working knowledge of the important things

Amy: Jewelry? Seriously? Sheldon, you are the most shallow, self-centered person I have ever met. Do you really think that another transparently manipul... Oh! It's a tiara! A tiara. I have a tiara! Put it on me, put it on me, put it on me, put it on me, put it on me, put it on me, put it on me.
Penny: You look beautiful
Amy: Of course I do. I'm a princess and this is my tiara.
Sheldon: You were right, the tiara was too much.

Penny: Not knowing's part of the fun.
Sheldon: Was that the motto of your community college?

Penny: What's AFK?
Sheldon: Away From Keyboard.
Penny: Oh, I see.
Sheldon: What does that stand for?

Penny: Oh, okay, look. THIS. NEVER. HAPPENED. Do you understand me?
Raj: (nodding)
Penny: Really?! Still can't talk to me?!

Bernadette: Gosh, Amy. I'm sensing a little hostility. Is it maybe because like Sheldon's work, your sex life is also theoretical?
Penny: Damn.
Amy: Well, at least, when we do make love, Sheldon won't be thinking about his mother.

Good morning, slut.

Sheldon: Is there any reason you're keeping this dead goldfish?
Penny: Damn, I forgot to feed him and that I had him.
Sheldon: Well, now, did you also have a dog? Because I found what appears to be a battery-operated chew toy.
Penny: Party's over. Party's over.

Penny: That's thinking ahead.
Sheldon: The alternative would be to think backwards.. and that's just remembering.

Penny: All right, try thinking about this -- Sheldon and Amy had sex.
Raj: Shut your ass.

Howard: Tell her I'm really sorry. And if she doesn't want to marry me, I get it. But what I really want her to know is the guy that she is really disgusted by is the guy that I'm disgusted by, too. But, that guy doesn't exist anymore; he's gone. And the reason is because of her. So, if this relationship is over, let her know that she made me a better man, and tell her thank you.
Penny: Oh my god, Howard! That's the most beautiful thing I've ever heard. And it came out of you.

Wolowitz [about his phone call]: Looks like I'm going to have sex tonight
Penny: His right hand is calling him?

TBBT Quotes

Amy, I excel at many things, but getting over you wasn't one of them.


(Singing) Thor and Dr Jones, Thor and Dr. Jones. One plays with lightening, the other plays with bones.

Howard and Raj