Leonard: I know what you are doing. You don't want me going on this research trip because you're afraid to be alone.
Sheldon: I'm not afraid to be alone. On the sea, it would be terrifying. Because of all the drowning.

Sheldon: I have not ruled it out.
Amy: Wow. Talk dirty to me.

See what happens when you let girls play D & D.

Sheldon: It would -- fun? Yeah, okay, three weeks ago, you brought crunchy peanut butter but now you want the girls to play D & D -- do you have a drug problem?
Leonard: What's the big deal?

Leonard: See, Howard is just as good a dungeon master as I am.
Sheldon: As good? You just got pantsed in the school yard four eyes.

Leonard: Sometimes change is good. You were worried about Zachary Quinto being the new Spock, but you ended up liking him.
Sheldon: Leonard, please, every time the topic of change comes up you throw Zachary Quinto in my face. I'm upset the mailman has a new haircut -- Zachary Quinto. I'm upset daylight savings time started -- Zachary Quinto. I'm upset daylight savings time ended -- Zachary Quinto. I'm saying this for the last time. Zachary Quinto was a weird, wonderful, unrepeatable event, so stop using him against me.

Professor Proton: Just- just call me Arthur.
Sheldon: Leonard ... Did you hear that? Professor Proton said I should call him Arthur. That means we're friends.

Sheldon: Leonard?
Leonard: What?
Sheldon: I still can't sleep.

Howard: How'd you get him to come to your house?
Sheldon: As Professor Proton says, "There is no problem you can't solve if you use your noggin."
Leonard: And, he wrote him a check.
Sheldon: Yeah, that too. A big check.

Amy: Missed one. Now your wish can't come true.
Sheldon: Lucky for you because I wished you were dead.

Sheldon: You don't know what it's like to feel completely frustrated. To have a-a desire build up within you and be denied any opportunity for release.
Amy: Yeah. Sounds like a drag.

Amy: All I'm saying is we live in a world where closure isn't always an op...
Sheldon: ...tion. Okay.

TBBT Quotes

Oh, Bernadette, please play my clarinet.

Raj's poem

Sheldon: I'll have a diet Coke.
Penny: Can you please order a cocktail? I need to practice mixing drinks.
Sheldon: Fine... I'll have a virgin Cuba Libre.
Penny: That's... rum and Coke without the rum.
Sheldon: Yes, and would you make it diet?