I'm sorry. What? I'm angry. What's wrong with having a lot of...
IZZIE: "I'm sorry."
GEORGE: "What? I'm angry. What's wrong with having a lot of sex if it makes you feel better?"
IZZIE: "Do you? Feel better?
GEORGE: "You know how you felt. Lying on the bathroom floor."
IZZIE: "Maybe you're not supposed to feel better."
GEORGE: "Izzie, you can't help me. I know you want to, but you can't. You can't help me."
IZZIE: "I have to let you go."
IZZIE: "Just one last thing. Life is short, George. Life is short and it sucks a lot of the time. But if being with Callie makes you happy, then go be with Callie."
IZZIE: "George, can I come in? I made you some cookies and brownies and muffins, of course. I always make muffins."
CALLIE: [runs out the door] "Thank God you're here. I can't take it anymore. Three times already tonight, and he's getting ready for a fourth."
IZZIE: "What are you talking about? Oh. Oh, ew."
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[narrating] "No one believes that their life will turn out just kind of okay. We all think we are going to be great. And from the day we decide to be surgeons, we are filled with expectation. Great expectations of who we will be, where we will go. And then... we get there."MEREDITH
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