Gideon: You've made some mistakes in your game play. Using von Strucker's son as a pawn when he shouldn't even be on the board yet.
Ward: You see, that's just typical of guys in your generation. You don't even know the game I'm playing. Von Strucker is more than just a pawn.
Gideon: And now he's a liability. He knows too much. Just tell me if I'm wrong. You burned that asset. S.H.I.E.L.D. is looking for him, which means so are you. And I know where you can find him.
Ward: And you'll just tell me that? Why?
Gideon: Sometimes you sacrifice a player to save the game. You just remember, when I come calling that I chose a side.

Hunter: Is that a person?
Daisy: Oh God.
Hunter: Is he dead?
Daisy: No they're monitoring him. He's alive.
Mack: But in, some kind of what... a coma?
Daisy: This is ATCU. This is where they're storing Inhumans they find. Like animals in cages.

Coulson: I heard what you did for me. I think it’s time that we remove this. [speaks to bracelet] Disengage bracelet.
Skye: Are you kidding me?
Coulson: I though you like that.

Fitz: What, you don't think I should help Simmons rescue Will?
Hunter: Do you think you should? He's the competition. If your girlfriend's ex wants to visit from Phoenix, you do not buy him a plane ticket.
Fitz: That's really specific. Anyway, this guy kept Simmons alive. I owe him. He deserves my help.

My entire life I've been searching for my parents, and my search ended with answers that are so much worse than I could have imagined.

Skye

Andrew: Hey, did Lincoln tell you where he is? I mean, he'd be safer here under our protection.
Daisy: I know, but he doesn't believe me. He won't tell me, but I'll let you know when he does.
Andrew: Great.

Andrew: Could be a real start toward legitimizing S.H.I.E.L.D. But it might help if you can present a successful Inhuman case. One that's not an extreme on either side.
Daisy: Joey Gutierrez is due for reassessment.
Andrew: I'd be more than happy to check in on him, see how he's progressing.
Daisy: Couldn't hurt.

Lincoln: I went looking for my friends. And those who aren't missing are dead.
Mack: You're telling me this, why?
Lincoln: Because you fought by my side against that thing. It eliminates you as a suspect.
Mack: Why would I be a suspect?
Lincoln: Because you're with S.H.I.E.L.D.
Mack: Okay, I'm not sure I'm following.
Lincoln: Lash is in S.H.I.E.L.D. and with your help I can prove it.

Simmons: Do you remember when we first met? I do. You were so quiet and pasty. So incredibly smart. Handsome. Quite a strange feeling, isn't it? Never wanting to be without someone. You must've been so annoyed me following you around all the time.
Fitz: No. Never.

Coulson: The ATCU is looking for a cure. I'm not suggesting that's for everyone, because it's not, but some people might want to...
Daisy: We are not a disease.
Coulson: I didn't say that you were.
Daisy: You can't just expect people to go through that kind of change and immediately have a handle on it. Do you remember how scared I was at first?
Coulson: Yes, I also remember you iced yourself so that you wouldn't hurt any of us. You've got to admit, things are getting out of hand.

Coulson: You agree with her. You think Skye is more than we can handle.
Agent May: Look, most of the time, I believe what I see, you know that but...
Coulson: But?
Agent May: You died. You were brought back, with a map to a city encoded in your DNA. Our team's first mission.
Coulson: We picked up Skye.
Agent May: Last week, we took her to that city. I can't help but remember what Lumley said. Wherever Skye goes...
Coulson: Death follows.

Coulson: Are you talking about fate?
Lady Sif: I am saying there are tides in the universe that you can not swim against.

Agents of S.H.I.E.L.D. Quotes

Kasius: Yo-Yo Rodriguez? How peculiar.
Yo-Yo: Says the space mime!

Sousa: Hey, what are you doing up?
Daisy: Why do you care?
Sousa: Because you don't.