Mal: You're only going to scare him.
Jayne: Pain is scary.

Lawrence: Okay, I can see you're not an idiot.
Jayne: Wish I could say the same, Lawrence, but this is disappointing as hell.

Zoe: Ever heard of Reavers?
Simon: Campfire stories - men gone savage at the edge of space.
Zoe: They're not stories.

Simon: What happens if they board us?
Zoe: If they take our ship, they'll rape us to death, eat our flesh and sew our skins into their clothing. And if we're very, very luck, they'll do it in that order.

Zoe: She still has the advantage over us.
Mal: Everyone always does. That's what makes us special.

Zoe: Sir, I need you to take the helm, please. I need this man to tear all my clothes off.
Wash: Work, work...

Simon: How do I know you won't kill me in my sleep?
Mal: You don't know me son, so let me explain this to you once. If I ever kill you, you'll be awake, you'll be facing me, and you'll be armed.

Mal: We're still flying.
Simon: That's not much.

I don't believe there's a power in the 'verse can stop Kaylee from being cheerfu

Mal

You got yourself a ship and you're a captain. Only I think you're still a sergeant. A man of honor in a den of thieves

Badger

Mal: Wheel never stops turning, Badger.
Badger: That only matters to the people on the rim.

Mal: I gotta know how close the Alliance is, exactly how much you told them before Wash scrambled your call. So I've given Jayne here the job of finding out.
Jayne: He was non-specific as to how.

Firefly Quotes

Mal: You're only going to scare him.
Jayne: Pain is scary.

Mal: I gotta know how close the Alliance is, exactly how much you told them before Wash scrambled your call. So I've given Jayne here the job of finding out.
Jayne: He was non-specific as to how.