CRISTINA: "There's a club. The Dead Dads Club. And you can't be in it until you're in it. You can try to understand, you can sympathize. But until you feel that loss... My dad died when I was nine. George, I'm really sorry you had to join the club."
GEORGE: "I... I don't know how to exist in a world where my dad doesn't."
CRISTINA: "Yeah, that never really changes."

When we say things like "people don't change" it drives scientist crazy because change is literally the only constant in all of science. Energy. Matter. It's always changing, morphing, merging, growing, dying. It's the way people try not to change that's unnatural. The way we cling to what things were instead of letting things be what they are. The way we cling to old memories instead of forming new ones. The way we insist on believing despite every scientific indication that anything in this lifetime is permanent. Change is constant. How we experience change that's up to us. It can feel like death or it can feel like a second chance at life. If we open our fingers, loosen our grips, go with it, it can feel like pure adrenaline. Like at any moment we can have another chance at life. Like at any moment, we can be born all over again.

Meredith

Callie: Did anyone ever think you two were a couple?
Meredith: No, because we screw boys like whores on tequila.
Cristina: Then we either try to marry them or drown ourselves.
Callie: Huh.

Derek: I wanna be with you forever, and you wanna be with me forever. In order to do that we need to make vows. A commitment. A contract. Give me a piece of paper.
Meredith: I don't! I... I... I don't. I have post its!
Derek: (takes the post its and a pen) Ok. What do we wanna promise each other?
Meredith: That you'll love me... even when you hate me.
Derek: To love each other, even when we hate each other. (writes it down) No running. Ever! (Mer smiles and comes and sits in front of him) Nobody walks out. No matter what happens.
Meredith: No running.
Derek: (writes it down) What else?
Meredith: That we'll take care of each other, even when we're old, and smelly, and senile. And... if I get Alzheimer's and forget you...
Derek: I will remind you who I am, every day. To take care when old, senile, and smelly (writes it down) This is forever. (signs it) Sign.
Meredith: This is our wedding. A post it? (smiles)
Derek: Mhmmm. If you sign it.
Meredith: (signs it, and hands it back. Has tears in her eyes) Now what?
Derek: Now I kiss the bride. (They kiss)
Meredith: (smiling) Married.
Derek: (smiling) Married. (sticks their post it in Mer's locker) You see that? (Mer nods and smiles) Plenty of time.

I gotta go. You stay here. You are a gifted surgeon with an extraordinary mind. Don’t let what he wants eclipse what you need. He’s very dreamy, but he’s not the sun. You are.

Cristina

Doesn't matter how tough we are, trauma always leaves a scar. It follows us home, it changes our lives, trauma messes everybody up, but maybe that's the point. All the pain and the fear and the crap. Maybe going through all of that is what keeps us moving forward. It's what pushes us. Maybe we have to get a little messed up, before we can step up.

Alex (narrating)

ADDISON: "There is a land called Passive Agressiva, and I am their queen."
DEREK: [smiles] "That's all I'm saying... except when you're shrieking about trout."

We spend our whole lives worrying about the future, planning for the future, trying to predict the future, as if figuring it out will cushion the blow. But the future is always changing. The future is the home of our deepest fears and wildest hopes. But one thing is certain when it finally reveals itself. The future is never the way we imagined it.

Meredith (closing voiceover)

"Okay, here it is, your choice... it's simple, her or me, and I'm sure she is really great. But Derek, I love you, in a really, really big pretend to like your taste in music, let you eat the last piece of cheesecake, hold a radio over my head outside your window, unfortunate way that makes me hate you, love you. So pick me, choose me, love me."

MEREDITH

It's good to be scared. It means you still have something to lose.

Richard

Sometimes the future changes quickly and completely, and we’re left with only the choice of what to do next. We can choose to be afraid of it, to stand there trembling not moving, assuming the worst that can happen or we step forward into the unknown and assume it will be brilliant.

Cristina

[to Richard] "Let's say you were drafted to a team that wasn’t your first pick. You know, you don't like the players. You hate the way they play the game. You even think the quarterback is full of crap. The quarterback's a pain in the ass you don't owe a damn thing to. But, it's your team. You don't quit. You don't talk to the press. You don't bitch to the coach. You just... you go out there on Sunday and you make the blocks and you take the hits and you play to win. You show up and you suit up and you play, because it's your freaking team."

ALEX

Grey's Anatomy Quotes

MEREDITH: "You don't get to call me a whore. When I met you, I thought I had found the person that I was going to spend the rest of my life with. I was done! All the boys and all the bars and all the obvious daddy issues, who cares? I was done. You left me. You chose Addison. I'm all glued back together now. I make no apologies for how I chose to repair what you broke. You don't get to call me a whore."
DEREK: "This thing with us is finished. It's over."
MEREDITH: "Finally."
DEREK: "Yeah, it's done."
MEREDITH: "It is done."

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)