DEREK: "We met at this bar, remember? We met and we, um, you said I'm just a girl, and I said I'm just a guy, and we started this thing. We started this thing. You didn't know anything about me. The good, the bad, the wife. You didn't even know my name. You didn't know me. I want you to know me. I want to start over from the beginning. So, hi, I'm Derek Shepherd."
MEREDITH: [pauses] "You walked away, and now it's too late. There's too much water under the thing, or whatever."
DEREK: "Meredith... Please."
MEREDITH: [sees Mark] "Hi, I'm Meredith Grey."
DEREK: "Very nice to meet you Meredith."
MEREDITH: "Nice to meet you too."

DEREK: "Hi, I'm Derek Shepherd."
MEREDITH: "What are you doing?"

PATIENT: "Man, I thought my brother and I had problems. But you two are morons."
CRISTINA: "Okay, well, swallowing Monopoly pieces wasn't exactly a genius move. You could've really hurt yourself."
PATIENT: "Well, I didn't, did I? Now my mom's gonna make my brother let me play Monopoly all I want."
CRISTINA: "And that makes you smart?"
PATIENT: "You're fishing through my poop. How smart does that make you?"

MEREDITH: "You came back."
VICKY: "I was heading home. I was on my way to the airport. You know you asked before why I came back the first time. You know I tried not to. Iwent on dates, I had a lot of great first dates with guys who were planning on staying guys, and you know you have a great date and you wanna go and tell your best friend about it... Well, my best friend is Daniel. Donna. And then a few bad dates... she’s my best friend. She knows me, she loves me. She's my husband. The end of the day it's Donna. Even though she hurts me and even when I hate her."
MEREDITH: "She’s the one you wanna talk to."

ADDISON: "Ted, Jamie... I need to talk to you. About the baby."
TED: "Dr. Montgomery..."
JAMIE: "You have to say it. I won't believe it, unless you say it. You have to say it."

VICKY: "Damnit, Daniel! Wake up!"
DONNA: "My name is Donna."

DEREK: "This is ridiculous. He's going to kill him."
PRESTON: "Don't be so sure. O'Malley's a scrapper."

"A slap fight?!"

GEORGE & ALEX

GEORGE: "Hey, have you noticed anything going on with Burke?"
ALEX: "No."
GEORGE: "Cause before I thought I saw - what are you doing? You don't use bait when you're casting. It's gonna fall off before it hits the water. Here -- what are you?"
ALEX: "She's sleeping with Sloan, dude."
GEORGE: "What?"
ALEX: "Callie. She's sleeping with Sloan."
GEORGE: "No she's not."
ALEX: "Yes. Torres is doing Sloan!"
GEORGE: "Take it back!"

RICHARD: "How long have you and Walter been together?"
JOE: "Ten years."
RICHARD: "Really?"
JOE: "Yeah. We're thinking about kids."
RICHARD: "That's a big step."
JOE: "Tell me about it. You have kids?"
RICHARD: "Me? No. I... I work all the time. Adele always said she didn't want to raise kids alone."
JOE: "Walter says the same thing... I'm always working. At the bar. If I'm not there, who's gonna run the place?"
RICHARD: "Right!"
JOE: "But... Walter's worth it. If I have to make a change I'll do it."

RICHARD: "Joe and Walter got tired of not catching any fish. They went for a hike. What do you make of that?"
PRESTON: "Joe and Walter?"
RICHARD: "Oh! No, no, no. Joe and Walter are great. I mean that we've not caught any fish."
DEREK: "Just one: fish generally don't like to go where there's a lot of noise."

DEREK: "This was my camping trip. I was going to come alone."
PRESTON: "Then why did you invite me?"
DEREK: "Because. It's a guy trip. You know, mountain men."
PRESTON: "You don't have any friends, do you?"
DEREK: "Of course I have friends."
PRESTON: "Guy friends?"
DEREK: "Yes! I just need peace.. space. I have a right to space. And you go and invite half the hospital."
PRESTON: "That's because I have guy friends."

Grey's Anatomy Quotes

[walking by Izzie's room]
Meredith: Hot.
Sadie: Horny.

Sexual sorbet? Hahaha! I love it.

Bailey