PATIENT: "You know the dream where you wake up in high school and you’re naked?"
IZZIE: "Yeah."
PATIENT: "Well I would really, really like to wake up. "

MEREDITH: "Why do people cheat?"
DEREK: "That’s a good question."
MEREDITH: "Why do you think she cheated on you? Were you different then? Were you a bad husband?"
DEREK: "I was... I was just a little absent. Not that that’s an excuse for her."
MEREDITH: "Do you think things would have been different if you had kids?"
DEREK: "Do I think she wouldn’t have cheated? I don’t know."

ADDISON: "Why are you here?"
MARK: "For one reason. To bring you home. I miss you Addison."
ADDISON: "I'm in love with my husband, Mark."
MARK: "He’s not in love with you. He’s in love with that intern. He’s not even trying to hide it. Why would you want to stick around for that?"

MARK: "Oh c’mon, you’re not even a little bit happy to see me?"
ADDISON: "Go home, whatever you came to do, just drop it and leave."
MARK: "Hey, we all made mistakes Addison, all three of us. But somehow... somehow, I lost my best friend and the woman I loved."
ADDISON: "Please, don’t say that."
MARK: "He doesn’t know how we felt. He doesn’t know you stayed with me after he left? How do you expect to work out a marriage if you can’t even be honest with him?"

IZZIE: "It’s like a beast, a beast that was asleep for a long, long time. And now the beast is wide-awake and wants to be fed and the food that Alex gave it -- it was good food George."
GEORGE: "Something needs to be done about your taste."

IZZIE: "You know when you don’t have sex for a while you sort of forget how good it is and you don't really need it as much?"
GEORGE: "Yeah, that doesn't happen to guys."

DEREK: "What the hell is he doing here?"
ADDISON: "I have no idea."

IZZIE: "I'm serious. We're friends and it didn’t work when we tried to be more than that, so, as fun as it was, it’s not gonna happen again."
ALEX: "Stop looking at me."
IZZIE: "I'm not looking at you, I'm rounding."
ALEX: "I'm rounding too."
IZZIE: "Fine."
ALEX: "Fine."

"And my husband wonders why I'm not interested in him anymore. I tell you, if he had any balls at all, he'd leave. But no, he plays stupid. Waiting for me to walk out. I came home the other day with a hickey, a hickey for God's sake! Like I'm some sort of sex-crazed teenager! And what does Thatcher do? Pretend he doesn’t see it."

ELLIS

ELLIS: "I'm exhausted."
MEREDITH: "Ugh... Me too."
ELLIS: "I was going at it all night in the on-call room, what's your excuse?"
MEREDITH [stunned] "Mom!"
ELLIS: "That man makes me purr like a kitten."
MEREDITH: "Mom!"
ELLIS: "When he's not making me growl like a tiger."
MEREDITH: "Stop!"

MEREDITH: "Ow. Ow. Ow."
IZZIE: "What are you doing?"
MEREDITH: "I'm inserting my banana bag. It sounds vaguely dirty, but it's not."

MEREDITH: "I seem to be drunk. I was off-duty."
MIRANDA: "So was I. Anybody else half in the bottle?"

Grey's Anatomy Season 2 Quotes

MEREDITH: "You don't get to call me a whore. When I met you, I thought I had found the person that I was going to spend the rest of my life with. I was done! All the boys and all the bars and all the obvious daddy issues, who cares? I was done. You left me. You chose Addison. I'm all glued back together now. I make no apologies for how I chose to repair what you broke. You don't get to call me a whore."
DEREK: "This thing with us is finished. It's over."
MEREDITH: "Finally."
DEREK: "Yeah, it's done."
MEREDITH: "It is done."

[narrating] "A wise man once said you can have anything in life if you will sacrifice everything else for it. What he meant is nothing comes without a price. So before you go into battle, you better decide how much you're willing to lose. Too often, going after what feels good means letting go of what you know is right, and letting someone in means abandoning the walls you've spent a lifetime building. Of course, the toughest sacrifices are the ones we don't see coming, when we don't have time to come up with a strategy to pick a side or to measure the potential loss. When that happens, when the battle chooses us and not the other way around, that's when the sacrifice can turn out to be more than we can bear."

MEREDITH