Sheldon [reading inscription]: "To Sheldon, sorry this took so long. Your friend, Wil Wheaton."
Wil: It's my last one and I want you to have it.
Sheldon: Look everyone, Wil Wheaton is my friend.

And you're going to have to choke back a hot sob of regret and humiliation as you mumble "I was, but I chose to go to a party thrown by the one kid from 'Stand by Me' that no one remembers."

Sheldon

Leonard: I'm going to a party. I'm not turning R2-D2 and C3PO over to the Empire!
Sheldon: Not yet.

... it was cooler for him to be the lower-left corner on Hollywood Squares.

Sheldon

Sheldon: This will just take a moment, it's on a five and a quarter inch floppy.
Amy: A floppy disk?
Sheldon: Well, I started the list when I was nine.

Penny: Wil Wheaton is Sheldon's mortal enemy.
Amy: Mortal enemy?
Penny: Mm-hmm.
Amy: Sheldon, I know you are a bit of a left-handed monkey wrench but... you really have a mortal enemy?
Sheldon: In fact, I have 61 of them.

Oh, boo-hoo, you're not going to space!

Bernadette

Howard: You know, there's a saying we have at NASA. What makes the right stuff so right is that it always comes home.
Bernadette: Stop talking, Howard.

Bernadette: Are those Russian rockets safe?
Howard: Well, I mean, safe as it can be when it was build by the good folks who brought you Chernobyl.

Until you either do not go or go to Wil Wheaton's party you are simultaneously my friend and not my friend. I'm characterizing this phenomenon as Schrodinger's Friendship.

Sheldon

It's gonna be another Wil Wheaton sausage fest.

Stuart

Okay if you're going to question the importance of an actor's signature on a plastic helmet from a movie based on a comic book then all of our lives have no meaning!

Stuart

The Big Bang Theory Season 5 Episode 5 Quotes

It's gonna be another Wil Wheaton sausage fest.

Stuart

Okay if you're going to question the importance of an actor's signature on a plastic helmet from a movie based on a comic book then all of our lives have no meaning!

Stuart