Despite their tendency to build Death Stars, I've always been more of an Empire man.

Sheldon

Penny: God, he's an ass when he drinks.
Wolowitz: He's an ass he doesn't. You just don't hear it.

Leonard: Amy is judgmental, sanctimonious, and frankly just obnoxious
Sheldon: So?
Leonard: So we already have you for all that.

Sheldon: One has to navigate a labyrinth of social nonsense before one could be fed here
Amy: Really? I assumed an establishment named Cheesecake Factory would function more efficiently.
Sheldon: It's how they lure you in. I believe it's called, "bait and switch."

I just run till I'm hungry, and then I stop for a bear claw.

Penny

Lenny: I though you hate dogs.
Sheldon: A dog-opus can play fetch with eight balls. No one can hate that.

Leonard: Penny, Steve Wozniack was one of the co-founders of Apple computer. He and Steve Jobs...
Penny: Yeah. I know who he is. I watch Dancing With the Stars.

Oh look! It's Leonard and R2-D-bag.

Wolowitz

Penny: Honey, have you ever run before?
Sheldon: Certainly. I've run from bullies, dogs, angry chickens and one particularly persistent PE teacher determined to bend me over and give me a scoliosis test.

Sheldon: I don't understand why you're not enjoying this. Together, in this car, with my enhanced capabilities, we're like 'Knight Rider.'
Leonard: Except, in Knight Rider, the car isn't a yammering sphincter.
Sheldon: You mock the sphincter, but, the sphincter is a class of muscle without which human beings couldn't survive. There are over 50 different sphincters in the human body. How many can you name?
Leonard: I was wrong. This is exactly like Knight Rider

Sheldon: You're 15th favorite technological visionary.
Steve Wozniak: Only fifteenth?
Sheldon: It's still six spots above Steve Jobs. I care neither for turtlenecks nor showmanship.

Penny: Can I ask you a question?
Sheldon: Given your community college education, I encourage you to ask as many as possible.

The Big Bang Theory Season 4 Quotes

You have broad hips and a certain corn-fed vigor. Is your womb available for rental?

Sheldon

At best, it's a modest leap forward from the technology that gave us Country Bear Jamboree.

Sheldon