Conrad and Nic host a game night with their friends. Cain and Bell are at a poker game and Cain and another doctor bet a patient Horace Dudley who has fantastic insurance. Cain wins and wins the patient. He wants to perform a risky surgery on Horace giving him a bionic spine.

Kit is upset when she finds out because Horace was her patient too. She wants to confront Cain about it, but Bell doesn't want her to. When she tells Horace what happened about being bet on, he's fine with it.

Cain does the surgery but when Horace has complications, no one can reach Cain. Irving asks Jessica to move in with him so they can host a game night but she declines until they get married. He feels Jessica has done more living and relationships then he has. AJ meets his mother for the first time and they all head out to dinner to get better acquainted, he is upset with her that she chose her career over her family.

Conrad tests his father to make sure he is ok as he finds out his name was on the list of patients the drug Hemopleatin was given too he is scared because both Nicolette and Conrad thinks the drugs kill people who have taken it, both him and Nic try to find a Dr that will give them access to patient files that will prove the drug Hemopleatin has a defect and is killing the cancer patients that was given the drug, she asks Devon but he says he won’t help it’s a violation.

Horace has trouble breathing his throat is closing up and swollen, Nicolette performs an emergency tracheotomy on him, Kit takes him into surgery against Bells advice not too as he fears what Cain will do to her. The surgery is a success leaving Dudley able to breathe and walk again. Kit offers to go into a joint venture with Cain opening a rehab treatment center and he agrees. Conrad’s dad offers to help him get the data he needs against the drug.

By taking him to a shareholder event for the CEO of kidney dialysis company Diacure, hoping he will let them look at their data from the drug. He agrees in exchange he wants Conrad to get his company a contract for a renal drug.

Devon and Irving have a patient who’s body is getting weak due to him keeping weight off on purpose to continue to be a horse jockey, he has a broken arm and even tho he’s allergic to gluten he eats cookies with them and it flares up his celiac, he refuses to stop but after a talk with the Drs and his girlfriend he agrees to give up riding the horse and choosing his health.

AJ decides to ask his mother Bonnie to come to the hospital in the middle of dinner and help to diagnose a patient of Okafor,the patient is a young girl who has declining cognitive issues, Bonnie and AJ arrive to help and Bonnie interacts with the girl asking her mother questions and discovers she may have Lyme disease, which thanks to Bonnie they have caught in time and start treatment immediately.

He thanks Bonnie and they share an emotional moment and hug and make plans to spend the holidays together. After spending the whole day at the hospital on shift all day due to being short staff Jessica is seen driving home and dozing off but she then crashed into a tree.