Bones Finale Tease

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According to this promo, "the season's biggest shock" is in store for Bones viewers. It will apparently go down on "The Beginning of the End," as teased here.
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Bones Season 5 Episode 22 Quotes

Brennan: I have the sense that everything's changing.
Booth: Not everything. Look, we're still partners, and Taffet, she's put away. You feel good about that, right?
Brennan: You almost died, Booth. That could happen again. What if next time I can't get to you?
Booth: That's not going to happen again.
Brennan: I envy your ability to substitute optimism for reality.

Caroline: So, how's your girlfriend holding up?
Booth: She's fine...she's not my girldfriend.
Caroline: Oh! So those looks between you...
Booth: Nothing.
Caroline: Right... hope you're more believable in the stand.