Sheldon's biggest dreams are about to come true.

Wil Wheaton (best known as Wesley Crusher from Star Trek: The Next Generation; and recently seen on Leverage) will guest star on the October 19 episode of The Big Bang Theory.

“As much as Sheldon loves Star Trek, Wil Wheaton is the only person associated with the franchise whom Sheldon has sworn eternal enmity toward,” the actor said when asked about by TV Guide Magazine about his role.

So, why does Sheldon have such animosity for Wheaton? The character apparently did not enjoy an autograph experience with Wil many years ago.

“The Wil I play in the Big Bang universe is not such a nice person,” Wheaton said. “But in real life, I go out of my way to be kind and patient. My motto is: ‘Don’t be a d---!’”

This premise, though, sounds like it sets up perfectly for a slew of hilarious The Big Bang Theory quotes.

Matt Richenthal is the Editor in Chief of TV Fanatic. Follow him on Twitter and on Google+.