Gossip Girl Spoilers: Major Breakup Ahead, Juliet to Blame!

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What's on tap for our favorite Upper East Side crew in the coming weeks?

Let's just say Juliet's meddling in "The Undergraduates" was just the start.

"Something wicked comes their way," EW reports this morning, and you can point the finger at Katie Cassidy. "Juliet’s butting in is going to lead to a major couple breaking up."

Chace Crawford and Katie Cassidy Picture

What's Juliet's grand plan and who will bear the brunt?

How will Juliet's agenda, whatever it might be, set a couple's breakup in motion? Which pair is it, and how will it come about? Theories and comments are encouraged below.

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.

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